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Articles

Page 11 of 374

  1. Non-small-cell lung cancer (NSCLC) is one of the most common malignant tumors, with poor prognosis and increasing osimertinib therapy resistance. Revealing mechanisms of NSCLC progression and therapy resistanc...

    Authors: Hongyang Sang, Jinlong Liu, Xifang Chen and Yingou Zeng
    Citation: BMC Cancer 2025 25:641
  2. The reliability of the M.D. Anderson Symptom Inventory-Multiple Myeloma Module (MDASI-MM) was evaluated through its Chinese translation among Chinese patients with multiple myeloma.

    Authors: Ting Wang, Weiwei Chen, Yingying Lin, LeiWen Tang, Junxiang Sun, Yao Ge, Yanke Mao and Huan Liu
    Citation: BMC Cancer 2025 25:640
  3. This study aimed to evaluate the effectiveness of different tracers´ application techniques for sentinel lymph node (SLN) detection in women with endometrial cancer undergoing laparotomy. Additionally, potenti...

    Authors: Borek Sehnal, Petr Waldauf, Radoslav Matej, Martin Hruda, Helena Robova, Jana Drozenova, Tomas Pichlik, Jan Zapletal, Lukas Rob and Michael J. Halaska
    Citation: BMC Cancer 2025 25:638
  4. Sepsis remains a leading cause of mortality in critically ill patients, particularly those with malignancies who face heightened risks due to immunosuppression and metabolic dysregulation. This study aimed to ...

    Authors: Yongshi Shen, Kangni Lin, Liuxin Yang, Peng Zheng, Wei Zhang, Jinsen Weng and Yong Ye
    Citation: BMC Cancer 2025 25:637
  5. Neoadjuvant chemotherapy with docetaxel, cisplatin plus 5-FU (DCF) has become the new standard of care for locally advanced esophageal squamous cell carcinoma (ESCC). In a real-world setting, the efficacy, rec...

    Authors: Mikako Tamba, Hiroki Osumi, Mariko Ogura, Shota Fukuoka, Akihiko Okamura, Jun Kanamori, Yu Imamura, Koichiro Yoshino, Shohei Udagawa, Takeru Wakatsuki, Eiji Shinozaki, Masayuki Watanabe, Kensei Yamaguchi, Keisho Chin and Akira Ooki
    Citation: BMC Cancer 2025 25:636
  6. The standard treatment for localized/locally advanced gastroesophageal adenocarcinoma (GEA) is radical surgery and peri-operative FLOT treatment (5-fluorouracil plus leucovorin, oxaliplatin, and docetaxel), bu...

    Authors: Vincenzo Nasca, Francesca Bergamo, Luisa Foltran, Lorenzo Antonuzzo, Katia Bencardino, Emanuela Dell’Aquila, Salvatore Corallo, Andrea Spallanzani, Oronzo Brunetti, Daniele Spada, Stefano Tamberi, Chiara Alessandra Cella, Antonio Avallone, Lorenzo Fornaro, Samantha Di Donato, Antonia Strippoli…
    Citation: BMC Cancer 2025 25:633
  7. The association between microRNA 17–92 cluster host gene (MIR17HG) polymorphisms and the risk of cancer has been evaluated in studies, here, we attempted to elucidate the relationship between 6 single nucleotide ...

    Authors: Binghua Tong, Zhaonan Zhang, Zhaowei Xu and Yangyang Yang
    Citation: BMC Cancer 2025 25:631
  8. Melanoma (SKCM) is an extremely aggressive form of cancer, characterized by high mortality rates, frequent metastasis, and limited treatment options. Our study aims to identify key target genes and enhance the...

    Authors: Songyun Zhao, Zihao Li, Kaibo Liu, Gaoyi Wang, Quanqiang Wang, Hua Yu, Wanying Chen, Hao Dai, Yijun Li, Jiaheng Xie, Yucang He and Liqun Li
    Citation: BMC Cancer 2025 25:630
  9. Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral and maxillofacial regions. Paeonol, derived from Moutan Cortex, has diverse pharmacological effects including anti-inflammatory a...

    Authors: Kang Yang, Baosen Yue, Huan Tian, Lu Wang, Xiao Yang and Weiying Zhang
    Citation: BMC Cancer 2025 25:629
  10. This study aimed to explore and compare the genomic characteristics and pathogenicity of Helicobacter pylori (H. pylori) strains derived from the gastric cancer (GC) and gastritis in the Chinese population.

    Authors: Peng-fei Kong, Yong-hao Yan, Yan-tao Duan, Yan-tian Fang, Yi Dou, Yong-hu Xu and Da-zhi Xu
    Citation: BMC Cancer 2025 25:628
  11. Areca nut (AN) was classified as a carcinogen by the International Agency for Research on Cancer (IARC) of the WHO in 2003. AN has the same carcinogenic components as cigarettes, such as benzo[a]pyrene (B[a]P)...

    Authors: Yixuan Li, Jing Zhou, Lirong Liu, Chaoyong Zhu, Ziyue Luo, Na Li, Pengfei Lyu, Jing Zhang, Tian Xie, Yipeng Ding and Sha Xiao
    Citation: BMC Cancer 2025 25:626
  12. This study aimed to learn the sketch of HPV infection and cervical lesions including squamous intraepithelial lesions (SIL) and cervical cancer in the population of patients with pelvic organ prolapse and to a...

    Authors: Yanjun Ge, Fan Wu, Yuchen Zhang, Xintao Wang and Guizhu Wu
    Citation: BMC Cancer 2025 25:624
  13. Gamma-delta (γδ) T cells are a critical component of the tumor microenvironment and have been recognized as a promising biomarker and target for cancer therapy. Increasing evidence suggests that γδT cells play...

    Authors: Guixin Wang, Shuo Wang, Wenbin Song, Chenglu Lu, Zhaohui Chen, Long He, Xiaoning Wang, Yizeng Wang, Cangchang Shi, Zhaoyi Liu, Yue Yu, Xin Wang, Yao Tian and Yingxi Li
    Citation: BMC Cancer 2025 25:623
  14. The effect of diffusion-weighted magnetic resonance imaging (DWI)-guided dose-painting intensity-modulated radiation therapy (DP-IMRT) on locally advanced recurrent nasopharyngeal carcinoma (NPC) remains uncle...

    Authors: Chao Tan, Yuyi Li, Xiaoyu Chen, Weichang Zhu, Cuihong Jiang, Lili He, Shuai Xiao, Changgen Fan, Xu Ye, Qi Zhao, Wenqiong Wu, Yanxian Li, Yanfang Qiu, Kailin Chen, Shulu Hu, Feng Liu…
    Citation: BMC Cancer 2025 25:622
  15. Cancer causes stress that impairs overall health of clients, their family members and health providers regardless of its stage. Despite the presence of various types of coping strategies to improve quality of ...

    Authors: Berhan Tsegaye Negash and Yitateku Alelign
    Citation: BMC Cancer 2025 25:621
  16. Malignant melanoma (MM) is a highly aggressive skin tumor with a rising incidence and poor prognosis. Although current clinical treatments, including surgery, targeted therapy, immunotherapy, and radiotherapy,...

    Authors: Wumei Zhao, Ziwen Chen, Wenxing Fu, Chenyan Ye, Haijing Fu, Tianyi Xu, Binghui Wu, Lina Chen and Shi-Jun Shan
    Citation: BMC Cancer 2025 25:620
  17. Immune checkpoint inhibitor (ICI) have been utilized in bone and soft tissues sarcoma patients under multiple circumstances in combination with surgeries and chemotherapy. Regretfully, immune-related adverse e...

    Authors: Qing Zhang, Zhe Wang, Xueqin Zeng, Yi Ding and Chen Wang
    Citation: BMC Cancer 2025 25:619
  18. Ubiquitin-specific protease 35 (USP35) has gained attention as a regulator in cancer progression. However, its specific role in kidney clear cell carcinoma (KIRC) remains unclear.

    Authors: Yadong Guo, Ziyou Lin, Zijing Zhou, Wentao Zhang, Shiyu Mao, Zezhi Shan, Pengfei Wu and Xudong Yao
    Citation: BMC Cancer 2025 25:617
  19. To investigate the prognostic value of the apparent diffusion coefficient (ADC) calculated from diffusion-weighted imaging (DWI) to cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal che...

    Authors: Xin Xin, Yongfang Tang, Man Lu, Jie Huang, Jian Shang, Lidan Yang, Lihuan Dai, Jinxue Yin, Jiansheng Li, Qibin Leng, Hongsheng Tang and Xi Zhong
    Citation: BMC Cancer 2025 25:616
  20. We aimed to investigate the diagnostic performance of biparametric MRI (bpMRI)-based radiomics in differentiating clinically significant prostate cancer (csPCa) among lesions categorized as Prostate Imaging Re...

    Authors: Feng Lu, Yanjun Zhao, Zhongjuan Wang and Ninghan Feng
    Citation: BMC Cancer 2025 25:615
  21. Managing advanced cancer can be psychologically distressing and burdensome for family caregivers and their care recipients. Innovations in the collection and modelling of passive data from personally-owned sma...

    Authors: J. Nicholas Odom, Kyungmi Lee, Erin R. Harrell, Kristen Allen Watts, Avery C. Bechthold, Sally Engler, Frank Puga, Natashia Bibriescas, Arif H. Kamal, Christine S. Ritchie, George Demiris, Alexi A. Wright, Marie A. Bakitas and Andres Azuero
    Citation: BMC Cancer 2025 25:614
  22. Everolimus is the only approved therapy for patients with advanced neuroendocrine tumors (NET) of lung and thymus and new treatment options are urgently needed. Expression of somatostatin receptor 2 (SSTR2) is...

    Authors: Jaume Capdevila, Virginia Pubul, Urbano Anido, Thomas Walter, Javier Molina-Cerrillo, Teresa Alonso-Gordoa, Rocio Garcia-Carbonero, Maria San-Roman-Gil, Belen Llana, Paula Jimenez-Fonseca, Marta Benavent Viñuales, Catherine Ansquer, Eric Baudin, Come Lepage, Maribel del Olmo-García, José Carlos Ruffinelli…
    Citation: BMC Cancer 2025 25:613
  23. Morocco’s national breast cancer screening program (NBCSP) was launched in 2010 in response to rising breast cancer incidence. The program comprises clinical breast examination (CBE) and diagnostic mammography...

    Authors: Melissa M. Carvalho, Aissatou Bah, Sofia Azrib, Robert A. Hiatt, Saber Boutayeb, Lahcen Belyamani, Amr S. Soliman and Mohamed Khalis
    Citation: BMC Cancer 2025 25:612
  24. Oral squamous cell carcinoma is a malignant tumor with high morbidity and mortality, and changes in microflora have a close relationship with tumor development. In this study, we tried to identify the changes ...

    Authors: Kaitong Wei, Yaqing Ma, Jing Xu, Hongyu Zheng, Lianping Xue, Yaojuan Chu, Yingying Shi, Zhi Sun and Qiang Sun
    Citation: BMC Cancer 2025 25:611
  25. The high occurrence of treatment resistance in patients with hormone receptor-positive (HR +) breast cancer is a global health concern. Thus, effective immunotherapy must be developed. The public neoantigens, ...

    Authors: Yukari Ando, Hiroko Miyadera, Hiroko Bando, Sachie Hashimoto, Emiko Noguchi and Hisato Hara
    Citation: BMC Cancer 2025 25:610
  26. The tumor microenvironment of breast cancer encompasses a broad spectrum of immune cell populations. These cell populations are biologically/clinically relevant to varying degrees. The causal relationship betw...

    Authors: Zhixuan Wu, Rongrong Zhang, Xue Wu, Xinyu Meng, Haodong Wu, Xiaowu Wang, Danni Zheng and Yanyan Shen
    Citation: BMC Cancer 2025 25:609
  27. Skull base chordoma is a rare and aggressive bone tumor with a poor prognosis. The basement membrane (BM) plays an pivotal role in tumor progression. However, the involvement of BM-related genes in assessing t...

    Authors: Tianhao Zhang, Mingxuan Li, Xing Liu, Sida Zhao, Tianshun Ma, Yide Liu, Xijia Zhang, Qian Liu, Jiwei Bai and Yazhuo Zhang
    Citation: BMC Cancer 2025 25:608
  28. Cervical cancer is a significant global health issue affecting women worldwide, necessitating prompt detection and effective management. According to the World Health Organization (WHO), approximately 660,000 ...

    Authors: Zahra Taghados, Zohreh Azimifar, Malihezaman Monsefi and Mojgan Akbarzadeh Jahromi
    Citation: BMC Cancer 2025 25:607
  29. There is a low incidence of gastric neuroendocrine carcinoma (G-NEC), but it is associated with particularly aggressive biological behaviours and poor prognosis compared with other gastric neoplasms. Our study...

    Authors: Kai Zhou, Xiao Hu, Xuesong Yang, Yan Wu, Ke Ji, Xin Ji, Ji Zhang, Xiaojiang Wu, ZhongWu Li, Anqiang Wang, Yusheng Wang and Zhaode Bu
    Citation: BMC Cancer 2025 25:606
  30. Minimally invasive thermal therapies show great prospect in non-small cell lung cancer (NSCLC) treatment. However, changes in immune cell populations following microwave ablation (MWA) in NSCLC microenvironmen...

    Authors: Run-Qi Guo, Yuan-Ming Li, Zhi-Xin Bie, Jin-Zhao Peng and Xiao-Guang Li
    Citation: BMC Cancer 2025 25:605
  31. This study aimed to evaluate the predictive efficacy of the prognostic nutritional index (PNI) in patients with intermediate and advanced hepatocellular carcinoma (HCC) treated with a regimen consisting of hep...

    Authors: Hao-Huan Tang, Ming-Qing Zhang, Zi-Chen Zhang, Chen Fan, Shu-Shu Li, Wei Chen and Wei-Dong Wang
    Citation: BMC Cancer 2025 25:603
  32. Identifying effective predictive strategies to assess the response of immune checkpoint inhibitors (ICIs)-based combination therapy in advanced hepatocellular carcinoma (HCC) is crucial. This study presents a ...

    Authors: Jun Xu, Junjun Li, Tengfei Wang, Xin Luo, Zhangxiang Zhu, Yimou Wang, Yong Wang, Zhenglin Zhang, Ruipeng Song, Li-Zhuang Yang, Hongzhi Wang, Stephen T. C. Wong and Hai Li
    Citation: BMC Cancer 2025 25:602
  33. As key mediators of antitumor immunity, CD8 + tumor-infiltrating lymphocytes present antigens and initiate robust immune responses against cancer cells. When stratified by location, CD8 + T lymphocytes were co...

    Authors: Ruijie Niu, Cheng Wang, Yiqun Xie, Shuangshuang Li, Qian Zhao, Yuqing Chang and Zubing Mei
    Citation: BMC Cancer 2025 25:601
  34. Culturally and linguistically diverse (CaLD) consumers and carers have been identified as experiencing high levels of unmet needs relating to information and support across the cancer journey. This review iden...

    Authors: Lisa Whitehead, Deborah Kirk, Pelden Chejor, Weiting Liu, Minh Nguyen, Caroline Balczer, Charlene Lan and Melissa Evans
    Citation: BMC Cancer 2025 25:599
  35. The Node Reporting and Data System (Node-RADS) offers a reliable framework for lymph node assessment, but its prognostic significance remains unexplored. This study aims to investigate the added prognostic val...

    Authors: Yan Sun, Lu Wen, Wang Xiang, Xiangtong Luo, Lian Chen, Xiaohuang Yang, Yanhui Yang, Yi Zhang, Sanqiang Yu, Hua Xiao and Xiaoping Yu
    Citation: BMC Cancer 2025 25:598
  36. Follow-up is essential especially for patients who are at a high risk of recurrence after radical resection of hepatocellular carcinoma (HCC). The aim of this study was to develop a predictive model aimed at i...

    Authors: Zichen Yu, Wenli Cao, Chengfei Du, Jie Liu, Liping Peng and Fangqiang Wei
    Citation: BMC Cancer 2025 25:597
  37. To establish prediction models to predict 2-year overall survival (OS) and stratify patients with different risks based on radiomics features extracted from magnetic resonance imaging (MRI) and computed tomogr...

    Authors: Nuo Yu, Yidong Wan, Lijing Zuo, Ying Cao, Dong Qu, Wenyang Liu, Lei Deng, Tao Zhang, Wenqing Wang, Jianyang Wang, Jima Lv, Zefen Xiao, Qinfu Feng, Zongmei Zhou, Nan Bi, Tianye Niu…
    Citation: BMC Cancer 2025 25:596
  38. Metastatic spinal tumors pose a significant challenge regarding intraoperative blood loss. Identifying risk factors for intraoperative blood loss is crucial for appropriate surgical planning and early interven...

    Authors: Xuedong Shi, Yunpeng Cui, Bailin Wang, Yuanxing Pan, Bing Wang, Yong Qin and Mingxing Lei
    Citation: BMC Cancer 2025 25:594
  39. Human oral tongue squamous cell carcinoma (OTSCC) is a prevalent form of head and neck squamous cell carcinoma (HNSCC), often presenting at an advanced stage with a grim prognosis. Traditional therapeutic appr...

    Authors: Shiyuan Liu, Tian Guan, Futian Yang, Honglei Zhang, Yao Yao, Jiman Huang, Pengfei Zhao, Wei Huang, Tailiang Wu, Hui Lin, Ting Fu, Shaoyu Chen, Pengzhan Dai, Zhechun Ding, Dongmei Chen, Wei Li…
    Citation: BMC Cancer 2025 25:593
  40. Metabolism and stemness-related genes (msRGs) are critical in the development and progression of lung adenocarcinoma (LUAD). Nevertheless, reliable prognostic risk signatures derived from msRGs have yet to be ...

    Authors: Wanrong Zheng, Chuchu Zhou, Zixin Xue, Ling Qiao, Jianjun Wang and Feng Lu
    Citation: BMC Cancer 2025 25:591
  41. We performed this meta-analysis to investigate the potential relationship between the polymorphism of the rs5743836 gene of toll-like receptors 9 (TLR9) and the risk of lymphoma.

    Authors: Minchao Yan, Qin Jin, Yan Zhou, Shuping Mo, Lun Tang, Gang Zhang, Qinyan Fu and Hui Zeng
    Citation: BMC Cancer 2025 25:584
  42. MicroRNAs (miRNAs) play a key role in regulating gene expression within the tumor microenvironment, influencing cancer progression and therapy response. Cancer-associated fibroblasts (CAFs) contribute to tumor...

    Authors: Parsa Golestannejad, Mohamadparsa Monkaresi, Farahnaz Zhian Zargaran, Mohammad Khosravani, Pouya Asgari, Hesam Mobaraki, Mansour Gorjizad, Saina Hasany, Aliakbar Senobari Ghezeljehmeidan, Sara Hemmati, Samaneh Zand, Parsa Ghasemi and Mahsa Asadi Anar
    Citation: BMC Cancer 2025 25:582

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