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Table 1 Baseline patient characteristics and predictive factors for endometrial carcinoma in patients with endometrioid intraepithelial neoplasia who underwent hysterectomy

From: Preoperative predictors of endometrial carcinoma in patients undergoing hysterectomy for endometrial intraepithelial neoplasia

 

EİN (n = 101), n (%)

EC (n = 71) n (%)

OR (95% CI)

P value

aOR (95% CI)

P value

Age

< 50

54 (53,5)

16 (22,5)

Reference

   

≥ 50

47 (46,5)

55 (77,5)

3.94 (2.00–7.79)

< 0,001

  

BMI (kg/ m²)

< 35

75 (74,3)

33 (46,5)

Reference

 

Reference

 

≥ 35

26 (25,7)

38 (53,5)

3.32 (1.74–6.33)

< 0,001

2.62 (1.28–5.37)

0.008

Parity

Nulliparous

5 (5,0)

8 (11,3)

Reference

   

multiparous

96 (95,0)

63 (88,7)

0.41 (0.12–1.31)

0.148

  

Menopausal status

premenopausal

65 (64,4)

19 (26,8)

Reference

 

Reference

 

postmenopausal

36 (35,6)

52 (73,2)

4.94 (2.54–9.60)

< 0,001

3.09 (1.50–6.39)

0.002

Hypertension

No

67 (66,3)

31 (43,7)

Reference

   

Yes

34 (33,7)

40 (56,3)

2.54 (1.36–4.74)

0.004

  

Diabetes mellitus

No

83 (82,2)

47 (66,2)

Reference

   

Yes

18 (17,8)

24 (33,8)

2.35 (1.15–4.78)

0.019

  

endometrium thickness

< 14

85 (84,1)

33 (46,5)

Reference

 

Reference

 

≥ 14

16 (15,9)

38 (53,5)

6.11 (3.01–12.43)

< 0,001

4.06 (1.89–8.75)

< 0.001

Ca125 (U/mL)

< 35

97 (96)

64 (90,1)

Reference

   

≥ 35

4 (4)

7 (9,9)

2.65 (0.74–9.42)

0.203

  
  1. Abbreviations: EIN, endometrial intraepithelial Neoplasia; aOR, EC, endometrium carcinoma; OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval; BMI, body mass index