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Table 1 Characteristics of the study population

From: Predictive value of intra-hepatectomy ICGR15 of the remnant liver for post-hepatectomy liver failure in hemi-hepatectomy: a prospective study

 

None-PHLF group

B/C PHLF group

P value

No. of patients

23

8

 

Demography related

 Male, (%)

17 (73.9)

8 (100.0)

0.298

 Age, mean (SD)

47.39 (8.69)

52.38 (8.45)

0.17

 BMI, mean (SD)

22.36 (2.99)

22.85 (2.01)

0.672

Liver function related

 INR, median [IQR]

0.99 [0.96, 1.02]

1.00 [0.93, 1.10]

0.803

 TB, (median [IQR])

10.80 [8.55, 15.30]

15.00 [13.01, 23.75]

0.109

 ICGR15-pre, median [IQR]

3.50 [3.27, 5.03]

4.50 [1.68, 8.93]

0.721

 Liver cirrhosis, (%)

13 (56.5)

5 (62.5)

1

 MELD, median [IQR]

2.70 [0.42, 5.03]

3.42 [1.34, 5.74]

0.685

 ALBI, median [IQR]

−2.85 [−3.03, −2.61]

−2.49 [−2.69, −2.28]

0.045

 FIB-4, median [IQR]

1.57 [0.96, 2.24]

2.70 [1.87, 3.05]

0.136

Tumor related

 AFP, median [IQR]

7.08 [3.13, 316.85]

33.20 [9.51, 77.97]

0.374

 Conversion therapy, (%)

4 (17.4)

2 (25.0)

0.634

 Single tumor, (%)

17 (73.9)

7 (87.5)

0.642

 Tumor size, max, median [IQR]

6.80 [4.00, 10.60]

9.25 [6.75, 12.50]

0.354

Hepatectomy related

 Right hepatectomy, (%)

16 (69.6)

6 (75.0)

1

 sFLR, median [IQR]

0.74 [0.67, 0.89]

0.73 [0.69, 0.76]

0.588

 ICGR15-intra, median [IQR]

9.20 [6.95, 13.65]

19.90 [15.70, 26.40]

0.002

 Duration of hepatectomy, min, median [IQR]

345.00 [272.50, 432.50]

384.50 [347.75, 496.00]

0.149

 Blood loss, ml, median [IQR]

400.00 [300.00, 600.00]

800.00 [450.00, 850.00]

0.127

 Duration of HPO, min, median [IQR]

38.00 [23.50, 47.25]

49.00 [19.00, 62.00]

0.438

 ICGR15-post, median [IQR]

17.00 [9.73, 25.65]

30.10 [14.15, 33.05]

0.226

Pathology related

 Ishak inflammation, median [IQR]

3.00 [3.00, 4.00]

5.50 [3.00, 6.00]

0.214

 Ishak fibrosis, median [IQR]

2.00 [2.00, 4.00]

2.50 [2.00, 4.50]

0.923

  1. Values were described as n (%), mean (SD), or median [IQR]
  2. Abbreviations: PHLF Post-hepatectomy liver failure, ICGR15 Intraoperative indocyanine green retention rate at 15 min, MELD End-stage Liver Disease, ALBI Albumin-Bilirubin, FIB-4 Fibrosis-4, sFLR Standardized future liver remnant, BMI Body mass index, calculated as weight in kilograms divided by height in meters squared, NLR Neutrophil to lymphocyte ratio, TB Total bilirubin, AFP Alpha-fetoprotein, HPO Hepatic portal occlusion, SD Standard deviation, IQR Interquartile range