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Table 2 Correlations between ADAM6 or PRSS1 and relevant quantitative variables in ALL, AML or all acute leukemia patients

From: Emerging roles of ADAM6 and PRSS1 as novel diagnostic/prognostic biomarkers for acute lymphoblastic and myeloid leukemia in adults

  

ALL (n = 36)

AML (n = 40)

All acute leukemia patients (n = 76)

Variable

 

ADAM6

PRSS1

ADAM6

PRSS1

ADAM6

PRSS1

Age

Rho

−0.233

−0.146

0.055

−0.384*

−0.054

−0.292*

p-Value

0.172

0.395

0.734

0.014

0.640

0.011

N

36

36

40

40

76

76

TLC

Rho

−0.324

0.211

0.382*

0.105

0.139

0.182

p-Value

0.054

0.216

0.015

0.519

0.232

0.115

N

36

36

40

40

76

76

Hemoglobin

Rho

0.152

−0.257

0.131

−0.043

0.157

−0.137

p-Value

0.375

0.130

0.419

0.793

0.176

0.239

N

36

36

40

40

76

76

Platelets

Rho

0.132

−0.370*

−0.113

−0.299

−0.045

−0.353**

p-Value

0.441

0.026

0.487

0.061

0.702

0.002

N

36

36

40

40

76

76

LDH

Rho

−0.618*

−0.258

-

-

−0.618*

−0.258

p-Value

0.018

0.374

-

-

0.018

0.374

N

14

14

-

-

14

14

ESR

Rho

0.491

0.465

-

-

0.491

0.465

p-Value

0.074

0.094

-

-

0.074

0.094

N

14

14

-

-

14

14

CRP

Rho

−0.269

0.000

-

-

−0.269

0.000

p-Value

0.353

1.000

-

-

0.353

1.000

N

14

14

-

-

14

14

Uric acid

Rho

−0.125

0.180

-

-

−0.125

0.180

p-Value

0.671

0.538

-

-

0.671

0.538

N

14

14

-

-

14

14

Blasts in BM aspirate

Rho

0.179

−0.009

-

-

0.179

−0.009

p-Value

0.296

0.960

-

-

0.296

0.960

N

36

36

-

-

36

36

Blasts in BM aspirate after induction chemotherapy

Rho

-

-

0.634**

0.254

0.634**

0.254

p-Value

-

-

0.006

0.325

0.006

0.325

N

-

-

17

17

17

17

Blasts in BM aspirate after 6 months

Rho

-

-

−0.167

−0.058

−0.167

−0.058

p-Value

-

-

0.604

0.857

0.604

0.857

N

-

-

12

12

12

12

MRD after induction chemotherapy

Rho

-

-

0.341

0.082

0.341

0.082

p-Value

-

-

0.181

0.756

0.181

0.756

N

-

-

17

17

17

17

MRD after 6 months

Rho

-

-

−0.142

−0.204

−0.142

−0.204

p-Value

-

-

0.696

0.571

0.696

0.571

N

-

-

10

10

10

10

ADAM6

Rho

-

−0.211

-

0.225

-

0.066

p-Value

-

0.218

-

0.163

-

0.574

N

-

36

-

40

-

76

PRSS1

Rho

−0.211

-

0.225

-

0.066

-

p-Value

0.218

-

0.163

-

0.574

-

N

36

-

40

-

76

-

  1. N Number, Rho Spearman’s rho