Preoperative plasma cell-free DNA chromosomal instability predicts microvascular invasion in hepatocellular carcinoma: a prospective study

Table 2 The AUC values, 95% CI and P-values of each chromosome arm losses and gains for MVI prediction in terms of Z-scores

Chromosome	AUC	95% CI	P value
chr1q	0.70	(0.551,0.856)	0.01
chr5p	0.68	(0.527,0.83)	0.02
chr8q	0.66	(0.505,0.822)	0.05
chr16p	0.66	(0.478,0.835)	0.06
chr4p	0.64	(0.462,0.815)	0.10
chr20p	0.63	(0.468,0.797)	0.11
chr7p	0.59	(0.436,0.737)	0.30
chr18p	0.59	(0.414,0.76)	0.30
chr21p	0.58	(0.421,0.736)	0.35
chr7q	0.57	(0.385,0.748)	0.43
chr20q	0.56	(0.386,0.737)	0.46
chr5q	0.55	(0.389,0.712)	0.55
chr17p	0.54	(0.373,0.7)	0.66
chr6p	0.53	(0.35,0.7)	0.76
chr11q	0.52	(0.346,0.683)	0.86
chr18q	0.51	(0.338,0.681)	0.91
chr15q	0.50	(0.327,0.678)	0.98
chr19p	0.50	(0.336,0.664)	1.00
chr19q	0.50	(0.336,0.664)	1.00
chr11p	0.49	(0.325,0.658)	0.92
chr17q	0.49	(0.316,0.663)	0.90
chr10p	0.49	(0.317,0.656)	0.87
chr9q	0.47	(0.316,0.627)	0.73
chr22q	0.47	(0.32,0.609)	0.67
chr3q	0.46	(0.286,0.636)	0.64
chr6q	0.46	(0.287,0.636)	0.64
chr16q	0.46	(0.278,0.639)	0.62
chr13q	0.44	(0.286,0.601)	0.50
chr3p	0.43	(0.252,0.616)	0.43
chr2p	0.43	(0.253,0.604)	0.39
chr1p	0.40	(0.244,0.546)	0.21
chr10q	0.39	(0.215,0.562)	0.18
chr9p	0.38	(0.218,0.541)	0.15
chr21q	0.38	(0.228,0.533)	0.15
chr12q	0.38	(0.195,0.561)	0.14
chr12p	0.38	(0.199,0.553)	0.14
chr8p	0.38	(0.205,0.546)	0.14
chr2q	0.37	(0.199,0.537)	0.12
chr4q	0.36	(0.215,0.506)	0.10
chr14q	0.31	(0.165,0.448)	0.02

Abbreviations: AUC, area under curve; CI, confidence interval; MVI, microvascular invasion

ISSN: 1471-2407