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Table 1 Patients’ demographic and clinical characteristics

From: Preoperative plasma cell-free DNA chromosomal instability predicts microvascular invasion in hepatocellular carcinoma: a prospective study

Parameters

Patients (n)

N = 74

N

%

Age, years

≥ 55

53

71.6%

 

< 55

21

28.4%

Gender

Male

59

79.73%

 

Female

15

20.27%

AFP (pre)

≥ 20 ng/mL

26

35.14%

 

< 20 ng/mL

48

64.86%

ALT (pre)

≥ 40 U/L

14

18.92%

 

< 40 U/L

59

79.73%

 

no detection

1

1.35%

AST (pre)

≥ 40 U/L

13

17.57%

 

< 40 U/L

60

81.08%

 

no detection

1

1.35%

HBV

positive

24

32.43%

 

negative

49

66.22%

 

no detection

1

1.35%

Tumor size

< 3 cm

42

56.76%

 

≥ 3 and < 5 cm

13

17.57%

 

≥ 5 cm

19

25.68%

Tumor count

multiple

12

16.22%

 

single

62

83.78%

Tumor encapsulation

yes

44

59.46%

 

no

30

40.54%

Tumor differentiation

well

5

6.76%

 

medium

60

81.08%

 

poor

7

9.46%

 

unknown

2

2.70%

MVI

0

59

79.73%

 

1

13

17.57%

 

2

2

2.70%

BCLC stage

0

17

22.97%

 

A

47

63.51%

 

B

5

6.76%

 

C

5

6.76%

Child-Pugh score

A

73

98.65%

 

unknown

1

1.35%

TACE treatment

yes

16

21.62%

 

no

58

78.38%

Primary

yes

52

70.27%

 

no

22

29.73%

Drinking history

yes

25

33.78%

 

no

49

66.22%

Smoking history

yes

28

37.84%

 

no

46

62.16%

  1. Abbreviations: AFP, alpha fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BCLC, Barcelona Clinic Liver Cancer; HBV, hepatitis B virus; MVI, microvascular invasion; TACE, trans-arterial chemoembolization. Unknown means the tumor was destroyed and not to be analyzed in terms of tumor differentiation; Child-Pugh score was missed due to the absence of certain indicators