Skip to main content

Table 3 Univariate and multivariate analyses of the DFS in all patients

From: The impact of EGFR mutation and PD-L1 status on the efficacy of postoperative radiotherapy in stage III-pN2 NSCLC

Characteristics

Univariate analysis

Multivariate analysis

HR (95%CI)

P-value

HR (95%CI)

P-value

Age

 

0.027

 

0.189

 ≤ 60

1

 

1

 

 > 60

1.741(1.066–2.845)

 

1.442(0.836–2.488)

 

Sex

 

< 0.001

 

0.346

 Female

1

 

1

 

 Male

2.444(1.486–4.019)

 

1.395(0.698–2.788)

 

Smoking status

 

< 0.001

 

0.936

 Never

1

 

1

 

 Former or current

2.376(1.502–3.758)

 

1.027(0.534–1.978)

 

Histology

 

0.009

 

0.867

 SCC

1

 

1

 

 ADC

2.162(1.214–3.848)

 

0.922(0.355–2.389)

 

Tumor size

 

0.027

 

0.264

 ≤3

1

 

1

 

 >3

1.670(1.061–2.629)

 

1.339(0.802–2.234)

 

Location

 

0.103

  

 Left lung

1

   

 Right lung

0.683(0.433–1.079)

   

Visceral pleura

 

0.732

  

 Negative

1

   

 Positive

1.085(0.680–1.733)

   

N1 nodes involved

 

0.301

  

 No

1

   

 Yes

1.301(0.790–2.143)

   

Involved N2 stations

 

0.309

  

 Single

1

   

 Multiple

1.273(0.799–2.028)

   

LNR

 

0.831

  

 ≤ 50%

1

   

 > 50%

1.064(0.602–1.879)

   

EGFR status

 

< 0.001

 

< 0.001

 Wild-type

1

 

1

 

 Mutant

0.369(0.221–0.615)

 

0.343(0.187–0.629)

 

PORT

 

0.076

 

0.016

 No

1

 

1

 

 Yes

0.581(0.320–1.058)

 

0.425(0.211–0.855)

 
  1. Abbreviations: HR, hazard ratio; CI, confidence interval; SCC, squamous cell carcinoma; ADC, adenocarcinoma; LNR, lymph node ratio; EGFR, epidermal growth factor receptor; PORT, postoperative radiotherapy
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us