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Table 2 Univariate and multivariate analyses of the OS in all patients

From: The impact of EGFR mutation and PD-L1 status on the efficacy of postoperative radiotherapy in stage III-pN2 NSCLC

Characteristics

Univariate analysis

Multivariate analysis

HR (95%CI)

P-value

HR (95%CI)

P-value

Age

 

0.026

 

0.235

 ≤ 60

1

 

1

 

 > 60

5.371(1.227–23.514)

 

2.525(0.547–11.661)

 

Sex

 

0.011

 

0.240

 Female

1

 

1

 

 Male

6.784(1.551–29.673)

 

3.002(0.480-18.782)

 

Smoking status

 

0.003

 

0.876

 Never

1

 

1

 

 Former or current

4.928(1.733–14.014)

 

1.115(0.283–4.396)

 

Histology

 

0.016

 

0.300

 SCC

1

 

1

 

 ADC

3.639(1.266–10.456)

 

2.317(0.473–11.358)

 

Tumor size

 

0.006

 

0.025

 ≤3

1

 

1

 

 >3

4.815(1.569–14.769)

 

4.538(1.212–16.988)

 

Location

 

0.466

  

 Left lung

1

   

 Right lung

1.448(0.535–3.915)

   

Visceral pleura

 

0.994

  

 Negative

1

   

 Positive

0.996(0.367–2.701)

   

N1 nodes involved

 

0.375

  

 No

1

   

 Yes

1.661(0.541–5.098)

   

Involved N2 stations

 

0.684

  

 Single

1

   

 Multiple

0.805(0.284–2.287)

   

LNR

 

0.804

  

 ≤ 50%

1

   

 > 50%

0.854(0.245–2.974)

   

EGFR status

 

0.012

 

0.097

 Wild-type

1

 

1

 

 Mutant

0.190(0.052–0.692)

 

0.303(0.074–1.240)

 

PORT

 

0.819

  

 No

1

   

 Yes

0.877(0.286–2.692)

   
  1. Abbreviations: HR, hazard ratio; CI, confidence interval; SCC, squamous cell carcinoma; ADC, adenocarcinoma; LNR, lymph node ratio; EGFR, epidermal growth factor receptor; PORT, postoperative radiotherapy