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Table 1 Patients clinicopathological characteristics of the whole cohort

From: The impact of EGFR mutation and PD-L1 status on the efficacy of postoperative radiotherapy in stage III-pN2 NSCLC

 

PORT(n = 61)

non-PORT(n = 190)

P-value

Age: no. (%)

0.501

 ≤ 60

29(47.5)

81(42.6)

 

 > 60

32(52.5)

109(57.4)

 

Sex: no. (%)

  

0.988

 Female

28(45.9)

87(45.8)

 

 Male

33(54.1)

103(54.2)

 

Smoking status: no. (%)

  

0.729

 Never

38(62.3)

123(64.7)

 

 Former or current

23(37.7)

67(35.3)

 

Histology: no. (%)

  

0.158

 SCC

6(9.8)

33(17.4)

 

 ADC

55(90.2)

157(82.6)

 

Tumor size: no. (%)

  

0.651

 ≤3

37(60.7)

109(57.4)

 

 > 3

24(39.3)

81(42.6)

 

Location: no. (%)

  

0.607

 Left lung

25(41.0)

85(44.7)

 

 Right lung

36(59.0)

105(55.3)

 

Visceral pleura: no. (%)

  

0.358

 Negative

44(72.1)

125(65.8)

 

 Positive

17(27.9)

65(34.2)

 

N1 nodes involved: no. (%)

  

0.083

 No

16(26.2)

73(38.4)

 

 Yes

45(73.8)

117(61.6)

 

Involved N2 stations: no. (%)

  

0.050

 Single

33(54.1)

129(67.9)

 

 Multiple

28(45.9)

61(32.1)

 

LNR: no. (%)

  

0.973

 ≤ 0.5

49(80.3)

153(80.5)

 

 > 0.5

12(19.7)

37(19.5)

 

EGFR status: no. (%)

  

0.024

 Wild-type

31(50.8)

62(32.6)

 

 Mutant

21(34.4)

101(53.2)

 

 Unknown

9(14.8)

27(14.2)

 

PD-L1 status: no. (%)

  

0.551

 Negative

18(29.5)

43(22.6)

 

 Positive

17(27.9)

59(31.1)

 

 Unknown

26(42.6)

88(46.3)

 
  1. Abbreviations: SCC, squamous cell carcinoma; ADC, adenocarcinoma; LNR, lymph node ratio; EGFR, epidermal growth factor receptor; PD-L1, programmed death-ligand 1; PORT, postoperative radiotherapy