Fig. 3

Flow cytometric analysis of MCF-7 cells after exposure to IC50 concentration of different substances. (A) Control treatment, (B) Free niosome, (C) Free solanine extract, (D) niosome containing solanine extract and (E) Tamoxifen. Q1 represents necrotic cells, Q2 represents late apoptotic cells, Q3 represents early apoptotic cells, and Q4 represents viable cells. The main discovery is that SN-NPs substantially enhanced apoptosis in MCF-7 cells relative to free solanine or free niosomes. Free solanine and free niosomes at their IC50 concentrations had no significant effect on the survival rate of MCF-7 cells in comparison to the control