Fig. 6

A Uniform Manifold Approximation and Projection (UMAP) and enriched heatmap of the overlap clusters. (A) UMAP of the four groups of patients conserved across all three clustering methods. The silhouette score for the clusters is 0.32. (B) Enriched heatmap of the differentially expressed genes across the overlap clusters. The clinical features sex, age, and tumour stage are given for each cluster. Age was the only clinical feature to be significantly different across clusters, with H4M2A3 (pink) having the youngest mean age