Prognostic and diagnostic value of PVR gene and protein levels, serum amylase, and urinary IGFBP-7 and TIMP-2 biomarkers in multiple myeloma

Table 5 Kaplan–Meier survival curves for OS according to different parameters

Parameter	Low expression			High expression			Log rank		Adjusted p-value (Bonferroni)
Parameter	Mean	Median	% End of Study	Mean	Median	% End of Study	χ2	p Value	Adjusted p-value (Bonferroni)
PVR Gene Expression	48.0	-	100.0%	44.84	-	84.0%	4.045*	0.044*	0.352
PVR Serum Level	50.20	-	96.0%	46.42	-	87.5%	1.108	0.293	1.000
Serum Amylase	49.0	-	100.0%	44.84	-	84.0%	4.045	0.044*	0.352
IGFBP-7	52.0	-	100.0%	44.68	-	83.6%	4.230*	0.040*	0.320
TIMP-2	50.0	-	100.0%	45.42	-	91.4%	0.177	0.674	1.000

^*Significant adjusted p-value. Bonferroni correction applied for 8 survival comparisons (adjusted α = 0.00625)

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