Table 11 Diagnostic performance of different biomarkers in multiple myeloma
Biomarker | AUC | 95% CI | Optimal Cutoff | Sensitivity (%) | Specificity (%) | P-value |
|---|---|---|---|---|---|---|
PVR Gene Expression | 0.92 | 0.87–0.97 | 2.5 (arbitrary units) | 80 | 82 | <0.001 |
PVR Serum Level | 0.83 | 0.76–0.90 | 120 ng/mL | 78 | 80 | <0.001 |
Serum Amylase | 0.93 | 0.83–0.87 | 150 U/L | 80 | 81 | 0.002 |
UIGFBP-7 | 0.85 | 0.70–0.86 | 0.5 (ng/mg) | 77 | 75 | 0.001 |
UTIMP-2 | 0.75 | 0.65–0.84 | 0.1 (ng/mg) | 70 | 65 | 0.012 |