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Fig. 6 | BMC Cancer

Fig. 6

From: Integrating single-cell and bulk RNA profiles to uncover glutamine metabolism’s role in prognosis and immune dynamics in multiple myeloma

Fig. 6

Experimental validation of model-centered genes in clinical samples. (A) qRT-PCR quantification of 10 prognostic genes (ANKRD28, DLD, FAM114A2, HSP90AA1, KIF13B, NFAT5, PGM3, SFT2D2, UBA2, and UBA5) in control (n = 9) versus MM (n = 11) samples. (B-D) Cell proliferation rates following siRNA-mediated knockdown of (B) DLD, (C) SFT2D2, and (D) UBA2 (***p < 0.01 vs. Scramble)

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BMC Cancer

ISSN: 1471-2407

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