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Table 1 Clinicopathological characteristics of patients receiving NACT

From: Patients with macroscopic lymph node metastasis expect poor prognosis after neoadjuvant chemotherapy in advanced ovarian cancer: a retrospective cohort study based on a single gynecological team

Characteristics

MLN group (n = 58)

NLN group (n = 108)

P value

Age (years), median (IQR)

52.00 (50.00, 61.75)

59.00 (51.00, 65.00)

0.028

BMI (kg/m2), median (IQR)

22.50 (20.26, 24.20)

22.42 (20.55, 25.19)

0.415

CCI

  

0.553

 0

47 (81.0%)

93 (86.1%)

 

 1

5 (8.6%)

9 (8.3%)

 

  > = 2

6 (10.3%)

6 (5.6%)

 

ECOG score

  

0.41

 0

32 (55.2%)

48 (44.4%)

 

 1

24 (41.4%)

53 (49.1%)

 

 2

2 (3.4%)

7 (6.5%)

 

Hydrothoraxa

  

0.795

 Yes

7 (12.1%)

11 (10.2%)

 

 No

51 (87.9%)

97 (89.8%)

 

Ascitesa

  

0.005

 Yes

17 (29.3%)

57 (52.8%)

 

 No

41 (70.7%)

51 (47.2%)

 

CA125a, median (IQR)

1429.0 (504.58, 3028.75)

1187.0 (609.80, 2935.50)

0.598

Pathology type

  

0.721

 Serous

54 (93.1%)

103 (95.4%)

 

 Non-serous

4 (6.9%)

5 (4.6%)

 

FIGO stage

  

0.001

 IIIC

29 (50.0%)

83 (76.9%)

 

 IV

29 (50.0%)

25 (23.1%)

 

SCS

  

0.004

 Low

6 (10.3%)

31 (28.7%)

 

 Intermediate

52 (89.7%)

73 (67.6%)

 

 High

0 (0.0%)

4 (3.7%)

 

BRCA mutationb

  

0.419

 Yes

11 (19.0%)

31 (28.7%)

 

 No

29 (50.0%)

55 (50.9%)

 

 Missing

18 (31.0%)

22 (20.4%)

 

NACT cycles

  

0.659

  < = 2

29 (50.0%)

60 (55.6%)

 

 3

24 (41.4%)

37 (34.3%)

 

  > = 4

5 (8.6%)

11 (10.2%)

 

NACT-IDS interval (days)c, mean (IQR)

29.00 (25.00, 36.50)

29.50 (24.75, 35.25)

0.995

Chemotherapy Lines before first PRRd

  

0.307

 1

11 (19.0%)

11 (10.2%)

 

 2

4 (6.9%)

4 (3.7%)

 

  > = 3

3 (5.2%)

0 (0.0%)

 

 Unknown

40 (69.0%)

93 (86.1%)

 
  1. The data are presented as percentages unless otherwise specified
  2. Abbreviations: NACT neoadjuvant chemotherapy, BMI body mass index, CCI Charlson comorbidity index, SCS surgical complex score, PRR platinum-resistant recurrence
  3. aRefers to characteristics presented at diagnosis;
  4. bMissing data were omitted when calculating the P value;
  5. cRefers to the duration between the end date of NACT and the date of IDS;
  6. dUnknown data refer to those without PRR events and were omitted when calculating the P value;