Fig. 5

(A-B) Receiver-operating characteristic curves for the ability of TBRblood (during-RT) and ΔTBRblood to predict radiation esophagitis after concurrent chemoradiotherapy. (A) Receiver-operating characteristic curves for the prediction of any grade of radiation esophagitis. (B) Receiver-operating characteristic curves for the prediction of grade 3 radiation esophagitis. (C) Correlogram: correlations between TBRblood, clinical and dosimetric variables (Spearman’s coefficient). Blue represents a positive correlation between two variables, and red represents a negative correlation between two variables. The stronger the correlation, the darker the color. (ΔTBRblood = TBRblood (during-RT) - TBRblood (pre-RT); Abbreviations: ECOG: Eastern Cooperative Oncology Group; V50: volume of esophagus receiving ≥ 50 Gy; V60: volume of esophagus receiving ≥ 60 Gy; RE: radiation esophagitis; RT: radiotherapy)