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Fig. 10 | BMC Cancer

Fig. 10

From: Comprehensive network pharmacology and experimentation to unveil the therapeutic efficacy and mechanisms of gypenoside LI in anaplastic thyroid cancer

Fig. 10

Gyp LI Affect the activation of the SRC / PI3K / AKT signaling pathway. (A-C) HSP90AA1, SRC and CASP3 mRNA expression in ATC cells after Gyp LI treatment. (D-G) Western blots of ATC cells treated with Gyp LI. The expression of proteins involved in the SRC/PI3K/AKT signaling pathway was monitored in cell lysates. GAPDH was utilized as a loading control for normalization. The Western blot data from three independent experiments were quantitatively analyzed using ImageJ software. Statistical significance was assessed using one-way ANOVA. (H-K) The Western blot results and corresponding statistical analyses of EMT-related proteins in ATC cells following treatment with Gyp LI

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BMC Cancer

ISSN: 1471-2407

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