Table 3 Univariate and multivariate COX analysis of iDFS in patients
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age (≤ 50 vs > 50) | 0.503 (0.135–1.873) | 0.306 | ||
Menopause status (pre vs post) | 0.508 (0.136–1.892) | 0.312 | ||
Lymphovascular invasion (yes vs no) | 0.516 (0.064–4.147) | 0.534 | ||
Laterality (left vs right) | 0.750 (0201–2.793) | 0.668 | ||
Tumor location (lateral vs central/medial) | 1.053 (0.263–4.211) | 0.942 | ||
Histopathologic type (ductal vs others) | 0.566 (0.071–4.533) | 0.592 | ||
Histological grade (II vs III) | 0.203 (0.051–0.812) | 0.024 | 0.773 (0.178–3.349) | 0.731 |
Pathological size (cm) (≤ 2 vs > 2) | 0.463 (0.124–1.726) | 0.252 | ||
Tumor subtype | < 0.001 | < 0.001 | ||
HER2 + (vs HR +/HER2-) | 12.183 (1.105–134.373) | 0.041 | 10.876 (0.909–130.116) | 0.059 |
TN(vs HR +/HER2-) | 58.478 (7.038–485.866) | < 0.001 | 74.066 (7.956–689.540) | < 0.001 |
Positive number of SLN (1 vs 2 ~ 3) | 0.416 (0.104–1.699) | 0.216 | ||
Surgical type (TM vs BCS) | 0.773 (0.207–2.884) | 0.702 | ||
Chemotherapy (yes vs no) | 23.348 (0.001–468721.034) | 0.533 | ||
Radiotherapy (yes vs no) | 0.401 (0.100–1.609) | 0.197 | ||
RNI (yes vs no) | 0.148 (0.018–1.180) | 0.071 | 0.089 (0.011–0.729) | 0.024 |