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Fig. 6 | BMC Cancer

Fig. 6

From: Comprehensive analysis illustrating the role of HOXB8 in head and neck squamous cell carcinoma: evidence from multi-omics analysis and experiments validation

Fig. 6

Biological enrichment analysis. Notes: A: DEGs analysis was performed in patients with high and low HOXB8 expression, 77 downregulated and 431 upregulated; B: ClueGO analysis of these DEGs; C: ssGSEA analysis was used to identify the correlation between specific pathways and HOXB8; D: GSEA analysis based on Hallmark gene set; E-G: GSEA analysis based on KEGG gene set; E: Western blot was used to detect the key protein involved in PI3K/AKT/mTOR and EMT signaling in the sh#ctl and sh#HOXB8 cells (SCC-4 cells)

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