Table 1 Distribution of patient demographics and histological and paraclinical biomarkers among patients with gastric cancer for mortality at 18 months (left) and 24 months (right)

Age M ± SD

59.7 ± 6.9

61.7 ± 8.5

0.12

Sex (Male/Female)

64/14

45/17

0.274

Tumor size M ± SD

4.06 ± 2.43

5.83 ± 2.86

0.007

Tumor size > 6

23

31

0.009

Tumor site

 Fundus

 Antrum

 Body

32

3

43

28

8

26

0.084

Tumor histology

 Intestine

 Diffuse

 Mix

55

13

10

34

12

16

0.10

Adenocarcinoma

48

44

0.162

Histology grade

 I

 II

 III

23

28

27

3

23

36

< 0.0001

Surgical Margin

22

36

< 0.0001

Vascular invasion

49

46

0.088

Peripheral invasion

38

42

0.015

Pathological tumor

 T0

 T1

 T2

 T3

 T4

2

1

21

29

25

0

1

0

10

51

< 0.0001

Regional lymph node

 N0

 N1

 N2

 N3

39

13

15

11

4

14

15

29

< 0.0001

TNM staging

 I

 II

 III

21

34

23

1

7

54

< 0.0001

Her 2 M ± SD

1.07 ± 1.05

2.00 ± 1.02

< 0.0001

Her 2 = > 2

23

44

< 0.0001

Vimentin M ± SD

1.75 ± 1.46

3.80 ± 1.12

< 0.0001

Vimentin = > 3

24

54

< 0.0001

COX M ± SD

1.87 ± 1.34

3.7 ± 1.44

< 0.0001

COX = > 3

19

50

< 0.0001

MMP7 M ± SD

1.62 ± 1.15

3.22 ± 1.36

< 0.0001

MMP7 = > 3

12

41

< 0.0001

Ki67 M ± SD

12.48 ± 4.97

20.19 ± 5.05

< 0.0001

Ki67 = > 13%

34

60

< 0.0001

P53 M ± SD

6.91 ± 10.30

16.25 ± 6.72

< 0.0001

P53 = > 6%

27

60

< 0.0001

C34 M ± SD

24.44 ± 8.69

35.62 ± 7.20

< 0.0001

CD34 = > 30%

25

50

< 0.0001

24-months Mortality

Survivors

(N = 41)

Number (%)

Non-survivors

(N = 99)

Number (%)

pvalue

Age

59.35 ± 6.76

61.09 ± 8.00

0.221

Sex (Male/Female)

30/11

79/20

0.283

Tumor size M ± SD

4.35 ± 2.00

5.49 ± 2.87

0.021

Tumor size > 6

13

41

0.164

Tumor site

 Fundus

 Antrum

 Body

16

2

23

58

20

46

0.495

Tumor histology

 Intestine

 Diffuse

 Mix

31

5

5

58

20

21

0.163

Adenocarcinoma

28

64

0.519

Histology grade

 I

 II

 III

15

16

10

11

35

53

< 0.0001

Surgical Margin

8

50

< 0.0001

Vascular invasion

24

71

0.69

Peripheral invasion

16

64

0.003

Pathological tumor

 T0

 T1

 T2

 T3

 T4

2

1

17

15

6

0

1

4

24

70

< 0.0001

Regional lymph node

 N0

 N1

 N2

 N3

27

10

3

1

16

17

27

39

< 0.0001

TNM staging

 I

 II

 III

19

19

3

3

22

74

< 0.0001

Her 2

0.50 ± 0.67

1.89 ± 1.03

< 0.0001

Her 2 = > 2

2

65

< 0.0001

Vimentin

0.90 ± 0.93

3.40 ± 1.31

< 0.0001

Vimentin = > 3

1

77

< 0.0001

COX

1.21 ± 1.09

3.24 ± 1.31

< 0.0001

COX = > 3

4

65

< 0.0001

MMP7

1.21 ± 1.00

2.79 ± 1.39

< 0.0001

MMP7 = > 3

2

51

< 0.0001

Ki67

9.33 ± 2.80

18.64 ± 5.19

< 0.0001

Ki67 = > 13%

5

89

< 0.0001

P53

2.19 ± 2.68

14.76 ± 9.64

< 0.0001

P53 = > 6%

4

83

< 0.0001

C34

19.02 ± 5.46

33.74 ± 7.68

< 0.0001

CD34 = > 30%

1

74

< 0.0001