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Table 2 Network meta-analysis comparison of 5 first-line therapies for PFS

From: Efficacy and safety of first-line CDK4/6 inhibitors plus AI therapy for patients with HR +/HER2- advanced breast cancer: a network meta-analysis

AI

0.51(0.38–0.69)

0.59(0.51–0.68)

0.57(0.48–0.67)

0.53(0.43–0.65)

1.96(1.45–2.64)

dalpi + Al

1.16(0.83–1.61)

1.12(0.79–1.57)

1.03(0.72–1.48)

1.70(1.46–1.96)

0.87(0.62–1.21)

palbo + Al

0.97(0.78–1.20)

0.89(0.69–1.15)

1.76(1.49–2.07)

0.90(0.64–1.26)

1.04(0.83–1.29)

ribo + AI

0.92(0.71–1.20)

1.90(1.54–2.34)

0.97(0.67–1.39)

1.12(0.87–1.45)

1.08(0.83–1.41)

abema + AI

  1. dalpi dalpiciclib, palbo palbociclib, abema abemaciclib, ribo ribociclib, AI aromatase inhibitor, PFS Progression-free survival