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Fig. 2 | BMC Cancer

Fig. 2

From: Deciphering a proliferation-essential gene signature based on CRISPR-Cas9 screening to predict prognosis and characterize the immune microenvironment in HNSCC

Fig. 2

Identification of PEGs in HNSCC cells. GSEA of hallmark pathways associated with HNSCC cell proliferation based on CERES scores from the DepMap database (a). Enrichment plots of the top 10 hallmark pathways ranked by NES (b). GO enrichment analysis of the identified 1,511 PEGs (c). KEGG pathway enrichment analysis of the identified PEGs (d). Abbreviations: PEGs, proliferation-essential genes; HNSCC, head and neck squamous cell carcinoma; GSEA, gene set enrichment analysis; DepMap, cancer dependency map; NES, normalized enrichment score; GO, gene ontology; KEGG, kyoto encyclopedia of genes and genomes

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BMC Cancer

ISSN: 1471-2407

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