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Fig. 2 | BMC Cancer

Fig. 2

From: Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the molecular feature of tumor-associated neutrophils of head and neck squamous cell carcinoma

Fig. 2

Construction and validation of neutrophil-related risk score using the TCGA cohort. (A) Forest plot of survival related neutrophil-related genes based on univariate Cox regression analysis. (B) The trajectory of each independent variable with lambda. (C) Plots of the produced coefficient distributions for the logarithmic series for parameter selection (lambda). (D) Visualization of gene-specific weights in the model score. (EH) Kaplan–Meier survival curve of the risk signature in TCGA training dataset (E), TCGA testing dataset (F), GSE65858 (G), and GSE41613 (H). (I-L) Time-dependent ROC curve of the risk signature in TCGA training dataset (I), TCGA testing dataset (J), GSE65858 (K), and GSE41613 (L)

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