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Fig. 5 | BMC Cancer

Fig. 5

From: PRDX1 knockdown promotes erastin-induced ferroptosis and impedes diffuse large B-cell lymphoma development by inhibiting the MAPK/ERK pathway

Fig. 5

PRDX1 knockdown impedes the DLBCL cell malignant behaviors by suppressing the MAPK/ERK pathway. A. The proliferation of cells was measured with the CCK-8 method after PRDX1 knockdown and anisomycin treatment. B. Cell apoptosis was detected using flow cytometry after the knockdown of PRDX1 and anisomycin treatment. C-D. Cell migration and invasion was assessed using the Transwell assays following PRDX1 knockdown and treatment with anisomycin. **P < 0.01 vs. si-NC group; ##P < 0.01 vs. si-PRDX1 group

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