Table 1 Clinical characteristics of treatment-related adverse events (AEs)
Characteristics | Chemotherapy alone (n, %) | Combination therapy (n, %) |
|---|---|---|
Gender | Â | Â |
 Female | 1088 (37.9) | 2024 (37.2) |
 Male | 1441 (50.2) | 3206 (58.9) |
 Missing | 342 (11.9) | 213 (3.9) |
Weight | Â | Â |
 <50 kg | 84 (2.9) | 201 (3.7) |
 50~100 kg | 759 (26.4) | 1797 (33.0) |
 >100 kg | 38 (1.3) | 33 (0.6) |
 Missing | 1990 (69.3) | 3412 (62.7) |
Age | Â | Â |
 <18 years | 3 (0.1) | 43 (0.8) |
 18-64.9 years | 1200 (41.8) | 2103 (38.6) |
 65–85 years | 1122 (39.1) | 2404 (44.2) |
 >85 years | 11 (0.4) | 9 (0.2) |
 Missing | 535 (18.6) | 884 (16.2) |
Type of reporter | Â | Â |
 Consumer | 481 (16.8) | 1203 (22.1) |
 Health-professional | 596 (20.8) | 916 (16.8) |
 Physician | 1076 (37.5) | 2600 (47.8) |
 Other health-professional | 453 (15.8) | 155 (2.8) |
 Pharmacist | 253 (8.8) | 568 (10.4) |
 Missing | 12 (0.4) | 1 (0.0) |
Reported countries | Â | Â |
 France | 708 (24.7) | 1199 (22.0) |
 United States | 405 (14.1) | 701 (12.9) |
 Italy | 321 (11.2) | 321 (5.9) |
 China | 255 (8.9) | 77 (1.4) |
 Japan | 227 (7.9) | 972 (17.9) |
 Germany | 102 (3.5) | 612 (11.2) |
 Canada | 85 (3.0) | 144 (2.7) |
 Other countries | 768 (26.7) | 1417 (26.0) |
Reported year | Â | Â |
 2017 | 254 (8.9) | 37 (0.7) |
 2018 | 523 (18.2) | 173 (3.2) |
 2019 | 440 (15.3) | 579 (10.6) |
 2020 | 345 (12.0) | 722 (13.3) |
 2021 | 213 (7.4) | 856 (15.7) |
 2022 | 326 (11.4) | 842 (15.5) |
 2023 | 374 (13.0) | 1073 (19.7) |
 2024 | 396 (13.8) | 1161 (21.3) |