Fig. 4

Functional characterization of different NK cell subsets in CLL. A-B Trajectories and heatmap of CLL-NK cells differentiating into CD56 dimNK and CD56brightNK cells, along with differential gene expression over pseudotime and enriched pathways. C Illustration of cell‒cell communication networks. D Recognition pairs of cell receptor‒ligand interactions. E Heatmap of cancer-related pathways enriched in NK cell subsets. F TF regulatory activity network inferred by SCENIC for different cell subsets