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Table 2 Univariate and multivariate analyses of recurrence-free survival in LUSC

From: Abnormal phosphorylation of human LRH1 at Ser510 predicts poor prognosis and promotes cell viability in lung squamous cell carcinoma

Variable

 

Univariate analysis

 

Multivariate analysis

HR

95%CI

P-value

 

HR

95%CI

P-value

Age

≧ 75

0.905

0.476–1.719

0.760

    

Gender

Female

1.043

0.409–2.664

0.930

    

Extent of resection

Lobectomy

0.469

0.229–0.961

0.039

 

0.194

0.077–0.485

< 0.001

Tumor size

>3 cm

1.770

0.945–3.313

0.074

    

pT

T2/T3/T4

1.907

0.984–3.697

0.056

 

1.591

0.595–4.257

0.355

Pathorogical grade

G2/G3

1.781

0.698–4.546

0.228

    

Vascular invasion

(+)

1.903

0.950–3.812

0.069

    

Lymphatic invasion

(+)

2.191

1.170–4.103

0.014

 

1.839

0.866–3.908

0.113

Pleural invasion

(+)

3.362

1.850–6.264

< 0.001

 

3.582

1.578–8.130

0.002

Lymph node metastasis

N1/N2

2.516

1.298–4.878

0.006

 

2.004

0.889–4.515

0.094

Pathological stage

II/III

1.534

0.825–2.855

0.177

    

hLRH1pS510

high

1.970

1.038–3.737

0.038

 

2.668

1.337–5.325

0.005

  1. HR, hazard ratio; CI, confidence interval
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