Skip to main content

Table 1 Relationship between clinicopathological risk factors and NPS

From: Prognostic significance of preoperative Naples prognostic score for disease-free and overall survival in oral cavity squamous cell carcinoma post-surgery

Characteristics

Group I (NPS 0)

N%

Group II (NPS 1–2)

N%

Group III (NPS 3–4)

N%

P*

Participants, N

132

312

145

 

Age (years)

52.0(40–69)

51.0(38–67)

59.0(43–72)

0.053

Gender

   

0.568

Male

59 (44.7%)

126(40.4%)

56(38.6%)

 

Female

73 (55.3%)

186(59.6%)

89(61.4%)

 

Grade

   

0.004

G1

51 (38.6%)

87(27.9%)

44(30.3%)

 

G2

51 (38.6%)

106(34.0%)

39(26.9%)

 

G3

30 (22.7%)

119(38.1%)

62(42.8%)

 

AJCC Stage

   

0.013

I

26 (19.7%)

58(18.6%)

25(17.2%)

 

II

38 (28.8%)

75(24.0%)

22(15.2%)

 

III

44 (33.3%)

127(40.7%)

59(40.7%)

 

IVa & IVb

24 (18.2%)

52(16.7%)

39(26.9%)

 

Perineural invasion

   

0.077

No

110 (83.3%)

279(89.4%)

131(90.3%)

 

Yes

22 (16.7%)

33(10.6%)

14(9.7%)

 

VI

   

0.652

No

118 (89.4%)

285(91.3%)

132(91.0%)

 

Yes

14 (10.6%)

27(8.7%)

13(9.0%)

 

Surgical margin

   

0.634

≥ 5 mm

118 (89.4%)

274(87.8%)

132(91.0%)

 

< 5 mm or postive

14 (10.6%)

38(12.2%)

13(9.0%)

 

ENE

   

0.664

Negative

111 (84.1%)

257(82.4%)

119(82.1%)

 

Positive

21 (15.9%)

55(17.6%)

26(17.9%)

 

DOI

   

0.003

< 10 mm

121 (91.7%)

260(83.3%)

114(78.6%)

 

≥ 10 mm

11 (8.3%)

52(16.7%)

31(21.4%)

 

Smoking

   

0.070

No

118 (89.4%)

273(87.5%)

119(82.1%)

 

Yes

14 (10.6%)

39(12.5%)

26(17.9%)

 

SIS

   

0.657

0

86 (65.2%)

231(74.0%)

93(64.1%)

 

1

30 (22.7%)

57(18.3%)

30(20.7%)

 

2

16 (12.1%)

24(7.7%)

22(15.2%)

 

ECOG PS score

   

0.031

0–1

105(79.5%)

248(79.5%)

100(69.0%)

 

2

27(20.5%)

64(20.5%)

45(31.0%)

 

SII

1200.5(688-1593.25)

1140.5(620.75–1586.0)

1138.0(614.0-1571.5)

0.787

PNI

72.0(53.0-96.75)

70.0(52.0–90.0)

70.0(46.0–96.0)

0.641

PLR

150.0(99.0-200.75)

149.0(93.0-216.5)

147.0(91.5–217.0)

0.917

NLR

2.43(1.60–3.32)

2.35(1.32–3.37)

2.42(1.42–3.31)

0.790

PAR

7.41(4.10–9.98)

6.46(3.44–9.51)

7.32(3.86–9.86)

0.941

TC

199.11(137.86-262.02)

196.39(130.66-247.55)

197.30(119.34-252.79)

0.359

LMR

5.25(2.53–7.66)

5.34(2.51–7.91)

5.77(2.75–7.75)

0.724

Hemoglobin (g/L)

98.5(92.0-136.7)

98.0(91.0-140.0)

97.0(91.0-142.0)

0.637

BMI (kg/m2)

22.0(19.6-25.68)

21.2(19.6–25.0)

21.1(19.6–25.0)

0.205

Albumin (g/L)

41.0(36.0-48.75)

42.0(35.0–49.0)

41.0(35.5–48.0)

0.862

ACCI

   

0.490

2–3

56(42.4%)

135(43.3%)

58(40.0%)

 

4–5

42(31.8%)

114(36.5%)

44(30.3%)

 

≥ 6

34(25.8%)

63(20.2%)

43(29.7%)

 

Adjuvant radiotherapy

   

0.076

No

81(61.4%)

210(67.3%)

75(51.7%)

 

Yes

51(38.6%)

102(32.7%)

70(48.3%)

 

Adjuvant chemotherapy

   

0.010

No

93(70.5%)

247(79.2%)

121(83.4%)

 

Yes

39(29.5%)

65(20.8%)

24(16.6%)

 
  1. *Normally distributed continuous variables are described as means ± SEs, and continuous variables without a normal distribution are presented as medians [interquartile ranges]. Categorical variables are presented as numbers (percentages)
  2. Abbreviations ACCI, age-adjusted Charlson comorbidity index; AJCC, American Joint Committee on Cancer; BMI, body mass index; DFS, disease-free survival; DOI, depth of invasion; ECOG PS, eastern cooperative oncology group performance status; ENE, extranodal extension; IQR, interquartile range; LMR, lymphocyte-to-monocyte ratio; NLR, neutrophil-to-lymphocyte ratio; NPS, Naples prognostic score; OS, overall survival; OCSCC, oral squamous cell carcinoma; PAR, platelet-to-albumin ratio; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutrition index; SII, systemic immune-inflammation index; SIS, systemic inflammation score; TC, total cholesterol; VI, vascular invasion
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us