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Table 5 The association between two SNPs genotypes and clinical characteristics of patients with BC in dominant model

From: The role of CDK8 gene polymorphisms in bladder cancer susceptibility and prognosis: a study in the Chinese Han population

Characteristics

rs17083838 Genotype

P valuea

rs7992670 Genotype

P valuea

GG

AG/AA

GG

AG/AA

Age

      

 ≤ 63 years old

101(84.2%)

19(15.8%)

0.81

46(38.3%)

74(61.7%)

0.18

 >63 years old

125(82.8%)

26(17.2%)

48(31.8%)

103(68.2%)

Sex

      

 Male

179(82.9%)

37(17.1%)

0.23

78(36.1%)

138(63.9%)

0.034

 Female

47(85.5%)

8(14.6%)

16(29.1%)

39(70.9%)

Smoke

      

 Smoker

120(85.1%)

21(14.9%)

0.26

42(29.8%)

99(70.2%)

0.0098

 Nonsmoker

106(81.5%)

24(18.5%)

52(40%)

78(60%)

Tumor stage

      

 MIBC

110(84%)

21(16%)

0.69

44(33.6%)

87(66.4%)

0.62

 NMIBC

116(82.9%)

24(17.1%)

50(35.7%)

90(64.3%)

Tumor grade

      

 High grade

136(84%)

26(16.1%)

0.68

55(34%)

107(66%)

0.99

 Low grade

90(82.6%)

19(17.4%)

39(35.8%)

70(64.2%)

Recurrence

      

 Recurrent

69(87.3%)

10(12.7%)

0.12

28(35.4%)

51(64.6%)

0.83

 Nonrecurrent

157(81.8%)

35(18.2%)

66(34.4%)

126(65.6%)

Metastasis

      

 Metastatic

38(79.2%)

10(20.8%)

0.19

19(39.6%)

29(60.4%)

0.38

 Nonmetastatic

188(84.3%)

35(15.7%)

75(33.6%)

148(66.4%)

  1. The P values in boldfaced indicates significant difference. a The P value was adjusted by age, sex, smoking status, tumor stage, tumor grade, recurrence status and metastasis status