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Table 1 Algorithm for management of elevated Portal Vein Pressure (PVP) in liver transplantation

From: Resection and partial liver transplantation from deceased donors with delayed total hepatectomy (RAPID procedure) for hepatocellular carcinoma: a national, multicenter, non-randomized, prospective trial

PVP—Portal Vein Pressure

Portal Modulation intervention

PVP ≤ 15 mmHg

No modulation required

PVP > 15 mmHg

Portal flow modulation is required until PVP is ≤ 15 mmHg

 

1. Somatostatin injection IV bolus 250 μg followed by intravenous 250 μg/hour

 

2. Splenic artery ligation

 

3. Partial portal vein ligation (banding)

 

4. Calibrated portocaval shunt

 

5. Splenectomy

  1. Flowchart illustrating the sequential interventions recommended to achieve and maintain portal vein pressure (PVP) ≤ 15 mmHg after graft reperfusion. Initial management begins with intravenous administration of somatostatin (bolus 250 µg followed by continuous infusion at 250 µg/hour). If target PVP remains unmet, subsequent steps include splenic artery ligation, partial portal vein ligation (banding), calibrated portocaval shunt, and ultimately splenectomy, progressing sequentially as needed until PVP ≤ 15 mmHg is achieved