Table 3 Univariate and multivariate logistic regression analysis in the derivation cohort
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Male | 1.062 (0.653–1.726) | 0.808 | ||
Age < 45 | 1.264 (0.801–1.993) | 0.314 | ||
HT | 0.814 (0.521–1.274) | 0.369 | ||
Tumor size ≧ 5 mm | 1.768 (1.084–2.886) | 0.022 | 1.871 (1.093-3.200) | 0.022 |
Multifocality | 1.119 (0.717–1.745) | 0.620 | ||
Unclear boundary | 1.682 (1.037–2.728) | 0.035 | 2.006 (1.176–3.421) | 0.011 |
Aspect ratio ≧ 1 | 1.260 (0.807–1.969) | 0.309 | ||
Blood flow | 0.883 (0.568–1.373) | 0.581 | ||
Calcification | 1.602 (1.028–2.497) | 0.037 | 2.359 (1.420–3.918) | < 0.001 |
Extrathyroidal extension | 2.368 (1.233–4.547) | 0.010 | 2.334 (1.144–4.761) | 0.020 |
High FN1 expression | 2.059 (1.275–3.325) | 0.003 | 2.588 (1.519–4.409) | < 0.001 |
Low MT-1 F expression | 2.336 (1.415–3.855) | < 0.001 | 2.410 (1.403–4.140) | 0.001 |
Low TFF3 expression | 2.209 (1.408–3.465) | < 0.001 | 2.307 (1.408–3.779) | < 0.001 |