Fig. 1

Differentially expressed mRNAs associated with the prognosis of PTMC. (A) Volcano plot of differentially expressed mRNAs between tumor tissues and normal tissues. Red spots represent up-regulated genes, and blue spots represent down-regulated genes. (B) Heatmap of differentially expressed mRNAs between tumor tissues and normal tissues. (C) OS-related mRNA selection using the least absolute shrinkage and selection operator (LASSO) regression. (D-F) Kaplan-Meier survival curves for PTMC patients with high or low expression of FN1 (D), MT-1Â F (E), and TFF3 (F) in the TCGA dataset