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Table 1 The preoperative clinical characteristics of T2 CRC patients (n = 787)

From: Identification of predictors for lymph node metastasis in T2 colorectal cancer: retrospective cohort study from a high-volume hospital

  

N0

n = 603 (%)

N1/2

n = 184 (%)

P-value

OR (95%CI)

Gender

   

0.003

0.472 (0.288–0.773)

 

Female

213 (72.4)

81 (27.6)

  
 

Male

390 (79.1)

103 (20.9)

  

Age a

 

61.47 ± 10.9

60.84 ± 11.2

0.460

 
    

0.328

 
 

< 50

69 (72.6)

26 (27.4)

  
 

≥ 50

534 (77.2)

158 (22.8)

  

BMI b

 

24.50 (4.50)

24.55 (4.20)

0.774

 

History of hypertension

 

0.639

 
 

No

395 (76.7)

120 (23.3)

  
 

Yes

208 (76.5)

64 (23.5)

  

History of diabetes

 

0.757

 
 

No

480 (76.6)

147 (23.4)

  
 

Yes

123 (76.9)

37 (23.1)

  

History of heart disease

 

0.044

0.468 (0.224–0.979)

 

No

543 (75.8)

173 (24.2)

  
 

Yes

60 (84.5)

11 (15.5)

  

History of abdominal operation

 

0.608

 
 

No

472 (76.7)

143 (23.3)

  
 

Yes

131 (76.2)

41 (23.8)

  

History of cancer

  

0.194

 
 

No

587 (76.9)

176 (23.1)

  
 

Yes

16 (66.7)

8 (33.3)

  

History of smoking

 

0.438

 
 

No

418 (76.6)

128 (23.4)

  
 

Yes

185 (76.8)

56 (23.2)

  

History of alcoholism

 

0.366

 
 

No

439 (76.9)

132 (23.1)

  
 

Yes

164 (75.9)

52 (24.1)

  

Family history of CRC

 

0.357

 
 

No

574 (76.9)

172 (23.1)

  
 

Yes

29 (70.7)

12 (29.3)

  

NLR b

 

1.88 (1.07)

1.77 (1.08)

0.372

 

LMR b

 

4.47 (2.46)

4.60 (2.46)

0.093

 

PLR b

 

124.72 (57.42)

122.86 (52.78)

0.042

0.989 (0.978-1.000)

CEA b

 

2.47 (2.39)

2.95 (2.45)

0.302

 

AFP b

 

2.72 (2.19)

2.76 (2.91)

0.670

 

CA125 b

 

8.88 (5.44)

8.66 (5.19)

0.412

 

CA19-9 b

 

9.81 (8.63)

10.68 (11.02)

0.176

 

CA153 b

 

8.49 (5.31)

8.47 (5.67)

0.638

 

CA724 b

 

2.07 (2.74)

2.02 (2.78)

0.158

 
  1. a Values are presented as mean ± SD
  2. b Values are presented as median (IQR)
  3. CRC, colorectal cancer; BMI, body mass index; NLR, neutrophil-to-lymphocyte ratio; PLR, platelets-lymphocyte-ratio; LMR, lymphocyte-to-monocyte ratio, CEA, carcinoembryonic antigen; AFP, alpha fetoprotein, CA, carbohydrate antigen