Fig. 8

Correlation between ADORA2B expression and immune cell infiltration in HNSC. Correlation analysis between ADORA2B expression and various immune cell types in HNSC (a). (b–p) Scatter plots showing the negative correlation between ADORA2B expression and specific immune cell populations, including eosinophils (b), mast cells (c), activated B cells (d), immature B cells (e), T follicular helper cells (f), MDSCs (g), type 1 T helper cells (h), macrophages (i), type 17 T helper cells (j), natural killer cells (k), effector memory CD8 T cells (l), monocytes (m), CD56dim natural killer cells (n), effector memory CD4 T cells (o), and regulatory T cells (p). Abbreviations: HNSC, head and neck squamous cell carcinoma; MDSCs, myeloid-derived suppressor cells