Fig. 2

Correlation between ADORA2B expression and clinical features in HNSC. Violin plots showing the relationship between ADORA2B expression and age (a), gender (b), lymphovascular invasion (c), and perineural invasion (d) in HNSC patients from TCGA datasets. (e-h) Association of ADORA2B expression with clinical T stage (e), clinical N stage (f), clinical M stage (g), and overall clinical stage (h). (i-l) Correlation between ADORA2B expression and pathological T stage (i), pathological N stage (j), pathological M stage (k), and overall pathological stage (l). Abbreviations: TCGA, The Cancer Genome Atlas; HNSC, head and neck squamous cell carcinoma. Statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns: not significant