Table 1 Baseline characteristics of early- and late-stage colon cancer cohorts in the UK Biobank
Baseline characteristica | Early stage (316) | Late stage (278) | P value |
|---|---|---|---|
Age at recruitment (year) | 61.27 (6.41) | 60.26 (6.78) | 0.06 |
Age at diagnosis (year) | 70.34 (7.40) | 67.90 (7.32) |  < 0.001 |
Sex | |||
 Male | 183 (57.9) | 145 (52.2) | 0.18 |
 Female | 133 (42.1) | 133 (47.8) |  |
 Ethnic (White %) | 304 (96.5) | 263 (96.0) | 0.91 |
 BMI | 27.98 (4.77) | 27.87 (4.61) | 0.77 |
 Year from baseline to diagnosis | 8.56 (3.79) | 7.15 (3.69) |  < 0.001 |
 Year from diagnosis to death | 5.99 (3.89) | 3.74 (3.85) |  < 0.001 |
Alcohol drinker status | |||
 Never | 19 (6.0) | 11 (4.0) | 0.54 |
 Previous | 13 (4.1) | 12 (4.3) |  |
 Current | 284 (89.9) | 252 (90.6) |  |
Smoking | |||
 Never | 146 (46.2) | 149 (53.6) | 0.12 |
 Previous | 139 (44.0) | 99 (35.6) |  |
 Current | 31 (9.8) | 26 (9.4) |  |
Survival status | |||
 Alive | 278 (88.0) | 106 (38.1) |  < 0.001 |
 Death | 38 (12.0) | 172 (61.9) |  |
Stageb | |||
 III | - | 63 (22.7) | - |
 IV | - | 215 (77.3) |  |
Metastasis type | |||
 Lymph node metastasis only | - | 63 (22.7) | - |
 Distant metastasis only | - | 120 (43.2) |  |
 Both types of metastases | - | 95 (34.2) |  |
Metastasis site | |||
 Liver and intrahepatic bile duct |  | 153 (55.0) | - |
 Lung |  | 83 (29.8) |  |
 Retroperitoneum and peritoneum |  | 80 (28.8) |  |