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Table 9 One-way COX regression analysis of PFS within the TD subgroup

From: Thyroid dysfunction as a predictor of PD- 1/PD-L1 inhibitor efficacy in advanced lung cancer

Variant

HR for PFS

95% CI

p

Baseline TSH level

0.983

0.834–1.159

0.840

Time of occurrence of TD (month)

0.944

0.876–1.018

0.137

Severity of TD

1.284

0.439–3.754

0.648

Regression of TD

0.816

0.384–1.733

0.597

Time of reversion (month)

1.010

0.637–1.601

0.577

Duration of TD (month)

0.907

0.844–0.975

0.008

  1. TD regression refers to the change in thyroid function after the occurrence of TD, which is classified into no change, conversion to other types of TD, and return to normal. The time of TD regression is defined as the period of time from the occurrence of TD to the return to normal or conversion to other types of TD. The duration of TD is defined as the time from the initial observation of TD to the return to normal, the date of progression, or cut-off
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BMC Cancer

ISSN: 1471-2407

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