Fig. 5

Pan-cancer analysis of associations between USP39 expression and immune-related features. (A) Heatmap showing correlations between USP39 expression and 150 immunomodulators categorized into five groups: chemokines, receptors, MHCs, immunoinhibitors, and immunostimulators. (B and C) Analysis of correlations between USP39 expression and tumor genomic features: tumor mutation burden (TMB) and microsatellite instability (MSI) across cancer types. *P < 0.05; **P < 0.01; ***P < 0.001