Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: Identification of USP39 as a prognostic and predictive biomarker for determining the response to immunotherapy in pancreatic cancer

Fig. 3

USP39-knockdown inhibits cell proliferation and migration and promotes cell death in human pancreatic cancer cells. (A) Western blot analysis revealed that the protein levels of USP39 significantly decreased in PANC-1 and MIAPaCa-2 cells when transfected with USP39 shRNA. β-Actin served as an internal control. (B) Representative results of colony formation in PANC-1 and MIAPaCa-2 cells. (C) USP39 knockdown suppressed migration capabilities in PANC-1 and MIAPaCa-2 cells (scale bar: 200 μm). (D) Representative results of the EdU assays (scale bar: 100 μm) in PANC-1 and MIAPaCa-2 cells. (E) Representative results of the cell death assay (scale bar: 100 μm) in PANC-1 and MIAPaCa-2 cells. (ns, not significant; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.)

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us