Fig. 2

Merging of GEO datasets and DEGs analysis. A-C Data distribution (A), density distribution (B) and UMAP distribution (C) after merging the data of GSE17025 and GSE63678, and removal of batch effect. D The volcano map shows the DEGs in EC tissues and non-cancerous tissues, with green representing significantly down-regulated genes, red representing significantly up-regulated expression genes, and black representing genes with insignificant expression differences. E The heat map shows the expression profiles of the top 20 up-regulated and top 20 down-regulated DEGs in EC and non-cancerous tissues. The red group represents normal tissue samples and the blue group represents EC samples. In the heat map, the deeper the red, the higher the expression level, and the deeper the blue, the lower the expression level