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Fig. 3 | BMC Cancer

Fig. 3

From: The acidic microenvironment promotes pancreatic cancer progression via the lncRNA-LOC100507424/E2F1/FOXM1 axis

Fig. 3

Transcriptional regulation of FOXM1 by LOC100507424. A-B: GEPIA analysis showing high FOXM1 expression in pancreatic cancer tissues and its correlation with poor prognosis. C: Dual luciferase activity assay showing the effect of LOC100507424 on FOXM1 promoter activity. D: Schematic diagram of primers 1–7 used for promoter region analysis. E: Electrophoresis gel image of ChIRP assay products. F: ChIRP assay identifying specific binding sites of LOC100507424 on the FOXM1 promoter. G: RT-qPCR detecting FOXM1 expression

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