Table 1 Descriptive statistics of triple-negative breast cancers (TNBCs) features, therapeutic variables and clinical outcomes stratified by detection method
| Â | Â | Method of detection | Â | |||
|---|---|---|---|---|---|---|
| Â | Â | Screen-detected | Symptomatic | Â | ||
| Â | Â | N | % | N | % | p-value |
Total | Â | 177 | 50.1% | 176 | 49.9% | Â |
Age at diagnosis (years) | Median (IQR*) | 62 (52–71) | 57 (45–73) | 0.028 | ||
Tumour size | T1-2 | 170 | 96.6% | 132 | 75% | < 0.001 |
| Â | T3-4 | 6 | 3.4% | 44 | 25% | |
Nodal status | Negative | 108 | 62.4% | 84 | 48% | 0.007 |
| Â | Positive | 65 | 37.6% | 91 | 52% | |
Stage | I-II | 141 | 85.4% | 111 | 63.8% | < 0.001 |
| Â | III-IV | 24 | 14.6% | 63 | 36.2% | |
Neoadjuvant chemotherapy | No | 137 | 79.2% | 96 | 55.2% | < 0.001 |
| Â | Yes | 36 | 20.8% | 78 | 44.8% | Â |
Pathological response | Complete | 7 | 22.6% | 15 | 22.4% | 0.997 |
| Â | Partial | 20 | 64.5% | 43 | 64.2% | |
| Â | Absent | 4 | 12.9% | 9 | 13.4% | |
Adjuvant chemotherapy | No | 51 | 31.3% | 60 | 34.5% | 0.533 |
| Â | Yes | 112 | 68.7% | 114 | 65.5% | |
Radiotherapy | No | 49 | 30.4% | 53 | 30.5% | 0.996 |
| Â | Yes | 112 | 69.6% | 121 | 69.5% | |
Type of surgery | Conservative | 117 | 74.0% | 94 | 56% | 0.001 |
| Â | Radical | 41 | 26.0% | 74 | 44% | |
Disease progression | No | 120 | 80.0% | 109 | 67.7% | 0.014 |
| Â | Yes | 30 | 20.0% | 52 | 32.3% | |
Death from any cause | No | 129 | 82.7% | 117 | 75.6% | 0.117 |
| Â | Yes | 27 | 17.3% | 41 | 24.4% | |
Follow-up (years) | Median (IQR*) | 3.7 (2.3–6.1) | 2.9 (1.5–5.1) | 0.001 | ||