Table 3 Univariable and multivariable Cox regression for OS
Univariable Model | Multivariable Model | |||||
|---|---|---|---|---|---|---|
Model 1 | Model 2 | |||||
Predictors | CHR (95% CI) | p-value | AHR (95% CI) | p-value | AHR (95% CI) | p-value |
Age | ||||||
≤ 40 | Reference | Reference | Reference | |||
41–50 | 4.39 (2.86; 6.73) | p < 0.001 | 3.10 (1.99; 4.81) | p < 0.001 | 3.20 (2.07; 4.94) | p < 0.001 |
51–65 | 6.57 (4.34; 9.95) | p < 0.001 | 3.40 (2.29; 5.27) | p < 0.001 | 3.29 (2.14; 5.05) | p < 0.001 |
> 65 | 14.38 (9.35; 22.12) | p < 0.001 | 6.26 (3.97; 9.88) | p < 0.001 | 7.00 (4.46; 11.01) | p < 0.001 |
Skin color | ||||||
White | Reference | Reference | Reference | |||
Black | 0.84 (0.45; 1.54) | p = 0.565 | 0.53 (0.28; 1.02) | p = 0.057 | 0.58 (0.31; 1.10) | p = 0.097 |
Other/Unknown | 0.66 (0.49; 0.89) | p = 0.007 | 0.81 (0.59; 1.13) | p = 0.212 | 0.88 (0.64;1.20) | p = 0.413 |
City of residence | ||||||
Other | Reference | Reference | Reference | |||
Cuiabá | 1.54 (1.12; 2.11) | p = 0.008 | 1.30 (0.94; 1.80) | p = 0.115 | 1.30 (0.94; 1.80) | p = 0.106 |
Várzea Grande | 0.99 (0.58; 1.70) | p = 0.999 | 1.06 (0.62; 1.82) | p = 0.833 | 1.07 (0.62; 1.83) | p = 0.818 |
Rondonópolis | 2.17 (1.37; 3.42) | p < 0.001 | 1.48 (0.93; 2.36) | p = 0.100 | 1.47 (0.92; 2.34) | p = 0.104 |
Sinop | 0.71 (0.22; 2.24) | p = 0.557 | 0.74 (0.23; 2.36) | p = 0.610 | 0.76 (0.24; 2.42) | p = 0.642 |
Histopathology type | ||||||
Squamous cell carcinoma | Reference | Reference | Reference | |||
Adenocarcinoma | 2.72 (1.58; 4.71) | p < 0.001 | 0.64 (0.36; 1.12) | p = 0.117 | 0.63 (0.36; 1.11) | p = 0.101 |
Malignant neoplasms | 22.89 (14.31; 36.60) | p < 0.001 | 5.86 (3.41; 10.09) | p < 0.001 | 5.61 (3.29; 9.55) | p < 0.001 |
Others | 2.84 (1.50; 5.38) | p < 0.001 | 0.72 (0.38; 1.39) | p = 0.333 | 0.69 (0.36; 1.33) | p = 0.268 |
Stage | ||||||
In situ | Reference | Reference | Reference | |||
Localized | 11.58 (8.20; 16.34) | p < 0.001 | 8.46 (5.72; 12.52) | p < 0.001 | 7.81 (5.40; 11.29) | p < 0.001 |
Metastatic | 22.89 (15.15; 34.60) | p < 0.001 | 12.21 (7.59; 19.66) | p < 0.001 | 12.36 (7.74; 19.74) | p < 0.001 |
Year of diagnosis | ||||||
2016–2018 | Reference | Reference | ||||
2001–2005 | 2.26 (1.34; 3.79) | p = 0.002 | 1.12 (0.62; 2.01) | p = 0.703 | ----------------------- | ------------ |
2006–2010 | 1.25 (0.71; 2.23) | p = 0.442 | 1.56 (0.62; 2.87) | p = 0.150 | ----------------------- | ------------ |
2011–2015 | 1.83 (1.05; 3.19) | p = 0.032 | 1.49 (0.83; 2.68) | p = 0.182 | ----------------------- | ------------ |
AIC | 2521.99 | 2520.48 | ||||