Fig. 4

Validation of metabolism-related prognostic signatures in TNBC using two independent cohorts. (A) Distribution of patient survival status and survival time according to the risk score in the GSE58812 dataset. (B) Expression heatmap of five key genes in the low- and high-risk groups within the GSE58812 dataset. (C) Kaplan‒Meier survival curves for the low- and high-risk groups derived from the GSE58812 dataset. (D) Time-dependent ROC analysis of the 2-, 4-, and 6-year overall survival (OS) probabilities in the GSE58812 dataset. (E) Distribution of patient survival status and survival time according to the risk score in the GSE21653 dataset. (F) Expression heatmap of five key genes in the low- and high-risk groups within the GSE21653 dataset. (G) Kaplan-Meier survival curves for the low- and high-risk groups derived from the GSE21653 dataset. (H) Time-dependent ROC analysis of the 2-, 4-, and 6-year overall survival (OS) probabilities in the GSE21653 dataset