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Table 3 Multivariate Cox regression analysis of prognostic factors for patients with lung cancer after LDCT screening

From: Prognostic factors of survival in patients with lung cancer after low-dose computed tomography screening: a multivariate analysis of a lung cancer screening cohort in China

Basic Model1

LDCT Screening Model2c

Factors

P-value

HRa

95% CIb

Factors

P-value

HRa

95% CIb

Gender

   

Gender

   

 Female

 

1

(Ref)

 Female

 

1

(Ref)

 Male

0.000

2.955

1.884–4.636

 Male

0.005

2.308

1.280–4.162

Age (years)

0.042

1.024

1.001–1.047

Personal monthly income (CNY)

   
    

 < 2000

 

1

(Ref)

Personal monthly income (CNY)

   

 20,00–3,999

0.021

0.595

0.382–0.926

 < 2000

 

1

(Ref)

 ≥ 4000

0.496

0.688

0.234–2.018

 20,00–3,999

0.024

0.703

0.518–0.954

Pathological type

   

 ≥ 4000

0.490

0.757

0.344–1.688

 Adenocarcinoma

 

1

(Ref)

Pathological type

   

 Small cell carcinoma

0.006

4.157

1.494–11.569

 Adenocarcinoma

 

1

(Ref)

 Squamous cell carcinoma

0.065

2.386

0.946–6.016

 Small cell carcinoma

0.002

2.545

1.389–4.661

 Othersd

0.279

1.355

0.782–2.349

 Squamous cell carcinoma

0.388

1.301

0.716–2.366

Stage

   

 Othersd

0.075

1.441

0.964–2.155

 0-I

 

1

(Ref)

Stage

   

 II

0.031

3.818

1.133–12.868

 0-I

 

1

(Ref)

 III

0.017

3.255

1.239–8.551

 II

0.230

1.806

0.688–4.741

 IV

0.011

3.144

1.297–7.621

 III

0.000

3.810

1.877–7.735

 Unknown

0.093

1.960

0.895–4.296

 IV

0.000

5.206

2.779–9.751

Surgery

   

 Unknown

0.002

2.426

1.386–4.244

 No

 

1

(Ref)

Surgery

   

 Yes

0.000

0.308

0.165–0.575

 No

 

1

(Ref)

KPSe

0.000

0.981

0.974–0.989

 Yes

0.000

0.364

0.231–0.574

Nodule property

   

KPSe

0.000

0.982

0.978–0.986

Solid nodule

 

1

(Ref)

    

 Part-solid nodule

0.974

1.018

0.348–2.983

    

 Non-solid nodule

0.038

0.470

0.231–0.959

    

 Uncertain nodule

0.066

0.649

0.409–1.029

    

Nodule size (mm)

0.030

1.015

1.001–1.028

  1. aHR: hazard ratio
  2. bCI: confidence interval
  3. cLDCT Screening Model: 258 participants with description of nodule size were involved in the LDCT screening model
  4. dOthers: including 11 cases of non-small cell lung carcinoma and 162 cases of pathologically unclassified lung cancer
  5. eKPS: Karnofsky performance score
  6. 1Involved gender (male, female), age (continuous), education (primary school or below, high school or above), personal monthly income (< 2,000¥, 2,000–3999¥, ≧4000¥), marital status (married, single/divorced/widow/others), smoking status (never, ever), previous COPD or tuberculosis (yes, no), pathological type (adenocarcinoma, small cell carcinoma, squamous cell carcinoma, others), stage (0-I, II, III, IV, unknown), surgery (yes, no), and KPS (continuous)
  7. 2Involved gender (male, female), age (continuous), education (primary school or below, high school or above), personal monthly income (< 2,000¥, 2,000–3999¥, ≧4000¥), marital status (married, single/divorced/widow/others), smoking status (never, ever), previous COPD or tuberculosis(yes, no), pathological type (adenocarcinoma, small cell carcinoma, squamous cell carcinoma, others), stage (0-I, II, III, IV, unknown), surgery (yes, no), KPS (continuous), nodule property (solid, part-solid, non-solid, uncertain), and nodule size (continuous)
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BMC Cancer

ISSN: 1471-2407

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