Table 4 Association of haplotypes and the risk of lung cancer
Haplotype | Frequency | Cases (n) | Controls (n) | OR (95%CI) | P |
|---|---|---|---|---|---|
CHRNA5 rs17486278 (A > C); CHRNA5 rs692780 (G > C) | |||||
 AG | 0.532 | 452 | 495 | 1.000 (ref.) | - |
 CG | 0.314 | 298 | 261 | 1.250 (1.014 ~ 1.542) | 0.036 |
 AC | 0.154 | 140 | 134 | 1.144 (0.874 ~ 1.497) | 0.326 |
CHRNA5 rs555018 (A > G); CHRNA3 rs3743078 (C > G) | |||||
 AC | 0.789 | 698 | 707 | 1.000 (ref.) | - |
 AG | 0.064 | 61 | 53 | 1.166 (0.795 ~ 1.709) | 0.432 |
 GG | 0.145 | 132 | 125 | 1.070 (0.820 ~ 1.396) | 0.620 |