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Table 1 Summary of Limit of Detection (LoD) for the OFA

From: Real-world application of targeted next-generation sequencing for identifying molecular variants in Asian non-small-cell lung cancer

Variant type

Reference standard

Number of variants tested

Detection threshold

SNV and Indel

OncoSpan (HD827) & HD753

20

VAF ≥ 5%

CNV

Seraseq CNV Mix Standard

6

 ≥ 5 copies

Gene Fusion

Seraseq Fusion RNA Mix v3

16

 ≥ 11 copies