Table 3 Related factors of HCC occurring 1–8 years after SVS

Sex(male,%)

 Female

1

 Male

1.892

(1.550–2.308)

< 0.0001

1.881

(1.536–2.303)

< 0.0001

Age(years)

 <40

1

 ≥40

8.016

(6.050–10.62)

< 0.0001

5.673

(4.23–7.608)

< 0.0001

Hypertension

 Absence

1

 Presence

1.947

(1.635–2.319)

< 0.0001

1.301

(1.069–1.583)

0.0090

DM

 Absence

1

 Presence

2.240

(1.848–2.714)

< 0.0001

1.172

(0.948–1.449)

0.1420

Dyslipidaemia

 Absence

1

 Presence

0.575

(0.427–0.775)

< 0.0001

0.548

(0.406–0.741)

< 0.0001

BMI (kg/m²)

 <25

1

 ≥25

1.260

(1.059–1.498)

0.0090

0.969

(0.812–1.157)

0.7280

γGT (U/L)

 <56

1

 ≥56

1.704

(1.457–1.993)

< 0.0001

1.110

(0.932–1.322)

0.2400

FIB-4 score

 ≤ 3.25

1

 >3.25

3.343

(2.858–3.911)

< 0.0001

1.823

(1.509–2.204)

< 0.0001

APRI score

 <2

1

 ≥2

1.927

(1.573–2.362)

< 0.0001

1.058

(0.84–1.333)

0.6320

ALBI score

 <-2.60)

1

 ≥-2.60

1.605

(1.371–1.879)

< 0.0001

0.863

(0.724–1.028)

0.0980

eGFR (mL/min/1.73 m²)

 ≥60

1

 <60

1.002

(0.740–1.357)

0.9900

0.824

(0.602–1.128)

0.2270

AFP (ng/ml)

 <5.0

1

 ≥5.0

2.541

(2.161–2.987)

< 0.0001

2.315

(1.923–2.787)

< 0.0001

HBeAg

 Absence

1

 Presence

0.492

(0.415–0.584)

< 0.0001

0.578

(0.484–0.691)

< 0.0001