Skip to main content

Table 4 Univariate Cox analysis and relative risk for death

From: Prognostic value of diffusion-weighted imaging to cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for patients with gastric cancer and peritoneal metastases

Characteristics

All patients

(n = 95)

 

CRS + HIPEC group

(n = 61)

 

CRS group

(n = 34)

 

β

HR (95%CI)

P value

β

HR (95%CI)

P value

β

HR (95%CI)

P value

Tumor site

         

Asystematic

0.38

1.47 (0.88, 2.44)

0.139

0.64

1.90 (0.98,3.67)

0.068

0.08

1.08 (0.41, 2.13)

0.859

Local

 

Reference

  

Reference

  

Reference

 

Pathological T stage

         

T4

0.52

1.69 (1.07, 2.66)

0.025

0.46

2.54 (1.02, 6.29)

0.045

0.80

2.23 (1.05, 4.76)

0.038

T2 or T3

 

Reference

  

Reference

  

Reference

 

Pathological N stage

         

N2 or N3

0.41

1.50 (1.04, 2.36)

0.046

0.53

1.69 (1.05, 3.01)

0.032

0.35

1.42 (0.68, 2.98)

0.355

N0 or N1

 

Reference

  

Reference

  

Reference

 

Histologic type

         

Signet ring or mucinous cell carcinoma

0.21

1.23 (0.68, 2.24)

0.497

0.17

1.18 (0.53, 2.64)

0.42

0.15

0.86 (0.35, 2.12)

0.741

Adenocarcinoma

 

Reference

  

Reference

  

Reference

 

Pathological differentiation

         

Poorly differentiated

0.66

1.92 (1.06, 3.50)

0.032

0.47

1.60 (0.79, 3.23)

0.188

0.88

2.81(1.23, 6.43)

0.014

Moderately or well differentiated

 

Reference

  

Reference

  

Reference

 

Combined systemic chemotherapy

         

No

0.40

1.50 (0.84, 2.66)

0.155

0.44

1.56 (0.73, 3.34)

0.254

0.45

1.56 (0.63, 3.85)

0.333

Yes

 

Reference

  

Reference

  

Reference

 

ADCmean

         

≤ 1.39 × 10− 3 mm2/s

0.75

2.11 (1.34, 3.35)

0.001

0.78

2.18 (1.20, 3.93)

0.01

0.91

2.48 (1.16, 5.32)

0.019

> 1.39 × 10− 3 mm2/s

 

Reference

  

Reference

  

Reference

 

ADCmin

         

≤ 0.77 × 10− 3 mm2/s

0.88

2.40 (1.51, 3.81)

<0.001

0.61

1.83 (1.03, 3.33)

0.039

1.55

4.72 (1.82, 12.15)

0.001

> 0.77 × 10− 3 mm2/s

 

Reference

  

Reference

  

Reference

 

ADCmax

         

≤ 2.59 × 10− 3 mm2/s

0.38

1.46 (0.93, 2.30)

0.103

0.37

1.44 (0.81, 2.57)

0.217

0.01

1.01 (0.48, 2.12)

0.98

> 2.59 × 10− 3 mm2/s

 

Reference

  

Reference

  

Reference

 
  1. Notes:
  2. CRS = cytoreductive surgery, HR = hazard ratio, HIPEC = hyperthermic intraperitoneal chemotherapy, ADC = apparent diffusion coefficient
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us