Fig. 6

Relationship between the ADCmin and OS in patients who received CRS, with or without HIPEC. Spearman’s correlation plots showed that the ADCmin was positively related to the OS period in all patients (a) and in CRS + HIPEC (b) and CRS groups (c), with the correlation coefficient rho (R) values of 0.470, 0.417, and 0.409, respectively. Kaplan–Meier analysis indicated that patients with ADCmin ≤ 0.77 × 10− 3 mm2/s had a significantly shorter OS period than that in those with ADCmean > 0.77 × 10− 3 mm2/s in all patients (HR = 2.40, P < 0.001) (d) and in CRS + HIPEC (HR = 1.83, P = 0.039) (e) and CRS groups (HR = 4.72, P = 0.001) (f). ADC, apparent diffusion coefficient; ADCmean, mean ADC; ADCmin, minimum ADC; CRS, cytoreductive surgery; HIPEC, hyperthermic intraperitoneal chemotherapy; OS, overall survival